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Prospective, randomized controlled trial on use of ropivacaine after robotic thyroid surgery: Effects on postoperative pain
ABSTRACT Background We evaluated the effects of ropivacaine for pain relief after robotic thyroid surgery. Methods One hundred eight patients scheduled for robotic thyroid surgery were randomized into ropivacaine (n = 54) or control (n = 54) groups. After surgery, 40 mL of 0.25% ropivacaine or 0.9%...
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| Published in: | Head & neck 2016-04, Vol.38 (S1), p.E588-E593 |
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| container_end_page | E593 |
| container_issue | S1 |
| container_start_page | E588 |
| container_title | Head & neck |
| container_volume | 38 |
| creator | Bae, Dong Sik Kim, Su-jin Koo, Do Hoon Paek, Se-Hyun Kwon, Hyungju Chai, Young Jun Choi, June Young Lee, Kyu Eun Youn, Yeo-Kyu |
| description | ABSTRACT
Background
We evaluated the effects of ropivacaine for pain relief after robotic thyroid surgery.
Methods
One hundred eight patients scheduled for robotic thyroid surgery were randomized into ropivacaine (n = 54) or control (n = 54) groups. After surgery, 40 mL of 0.25% ropivacaine or 0.9% saline (control) was instilled into the skin flap. Postoperative pain intensity (visual analog scale [VAS]), analgesic requirements (fentanyl), and adverse events were assessed at 1, 2, 4, 8, 16, and 24 hours postoperatively.
Results
One hundred three patients completed the study protocol. VAS scores were lower in the ropivacaine group than the control group (p = .010); however, VAS scores were not significantly different after 8 hours postoperatively. Total analgesic consumption was higher in controls than ropivacaine‐treated patients (p = .01). Adverse events did not differ between the 2 groups.
Conclusion
Ropivacaine instillation after robotic thyroid surgery reduces acute postoperative pain and analgesic requirements without adverse events. © 2015 Wiley Periodicals, Inc. Head Neck 38: E–E, 2016 |
| doi_str_mv | 10.1002/hed.24045 |
| format | article |
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Background
We evaluated the effects of ropivacaine for pain relief after robotic thyroid surgery.
Methods
One hundred eight patients scheduled for robotic thyroid surgery were randomized into ropivacaine (n = 54) or control (n = 54) groups. After surgery, 40 mL of 0.25% ropivacaine or 0.9% saline (control) was instilled into the skin flap. Postoperative pain intensity (visual analog scale [VAS]), analgesic requirements (fentanyl), and adverse events were assessed at 1, 2, 4, 8, 16, and 24 hours postoperatively.
Results
One hundred three patients completed the study protocol. VAS scores were lower in the ropivacaine group than the control group (p = .010); however, VAS scores were not significantly different after 8 hours postoperatively. Total analgesic consumption was higher in controls than ropivacaine‐treated patients (p = .01). Adverse events did not differ between the 2 groups.
Conclusion
Ropivacaine instillation after robotic thyroid surgery reduces acute postoperative pain and analgesic requirements without adverse events. © 2015 Wiley Periodicals, Inc. Head Neck 38: E–E, 2016</description><identifier>ISSN: 1043-3074</identifier><identifier>EISSN: 1097-0347</identifier><identifier>DOI: 10.1002/hed.24045</identifier><identifier>PMID: 25782919</identifier><language>eng</language><publisher>United States: Blackwell Publishing Ltd</publisher><subject>acute pain ; Adult ; Amides - therapeutic use ; Analgesics - therapeutic use ; Anesthetics, Local - therapeutic use ; bilateral axillo-breast approach (BABA) ; Double-Blind Method ; Female ; Humans ; Male ; Middle Aged ; Pain, Postoperative - drug therapy ; postoperative pain ; Prospective Studies ; Robotic Surgical Procedures ; robotic thyroid surgery ; ropivacaine ; Thyroid Gland - surgery ; Thyroid Neoplasms - surgery ; Thyroidectomy</subject><ispartof>Head & neck, 2016-04, Vol.38 (S1), p.E588-E593</ispartof><rights>2015 Wiley Periodicals, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3635-e680c86b91a6d0b294dfb5a673f785f55da345a4bf8198d8b79bf811469aaa1c3</citedby><cites>FETCH-LOGICAL-c3635-e680c86b91a6d0b294dfb5a673f785f55da345a4bf8198d8b79bf811469aaa1c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25782919$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bae, Dong Sik</creatorcontrib><creatorcontrib>Kim, Su-jin</creatorcontrib><creatorcontrib>Koo, Do Hoon</creatorcontrib><creatorcontrib>Paek, Se-Hyun</creatorcontrib><creatorcontrib>Kwon, Hyungju</creatorcontrib><creatorcontrib>Chai, Young Jun</creatorcontrib><creatorcontrib>Choi, June Young</creatorcontrib><creatorcontrib>Lee, Kyu Eun</creatorcontrib><creatorcontrib>Youn, Yeo-Kyu</creatorcontrib><title>Prospective, randomized controlled trial on use of ropivacaine after robotic thyroid surgery: Effects on postoperative pain</title><title>Head & neck</title><addtitle>Head Neck</addtitle><description>ABSTRACT
Background
We evaluated the effects of ropivacaine for pain relief after robotic thyroid surgery.
Methods
One hundred eight patients scheduled for robotic thyroid surgery were randomized into ropivacaine (n = 54) or control (n = 54) groups. After surgery, 40 mL of 0.25% ropivacaine or 0.9% saline (control) was instilled into the skin flap. Postoperative pain intensity (visual analog scale [VAS]), analgesic requirements (fentanyl), and adverse events were assessed at 1, 2, 4, 8, 16, and 24 hours postoperatively.
Results
One hundred three patients completed the study protocol. VAS scores were lower in the ropivacaine group than the control group (p = .010); however, VAS scores were not significantly different after 8 hours postoperatively. Total analgesic consumption was higher in controls than ropivacaine‐treated patients (p = .01). Adverse events did not differ between the 2 groups.
Conclusion
Ropivacaine instillation after robotic thyroid surgery reduces acute postoperative pain and analgesic requirements without adverse events. © 2015 Wiley Periodicals, Inc. Head Neck 38: E–E, 2016</description><subject>acute pain</subject><subject>Adult</subject><subject>Amides - therapeutic use</subject><subject>Analgesics - therapeutic use</subject><subject>Anesthetics, Local - therapeutic use</subject><subject>bilateral axillo-breast approach (BABA)</subject><subject>Double-Blind Method</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Pain, Postoperative - drug therapy</subject><subject>postoperative pain</subject><subject>Prospective Studies</subject><subject>Robotic Surgical Procedures</subject><subject>robotic thyroid surgery</subject><subject>ropivacaine</subject><subject>Thyroid Gland - surgery</subject><subject>Thyroid Neoplasms - surgery</subject><subject>Thyroidectomy</subject><issn>1043-3074</issn><issn>1097-0347</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><recordid>eNp1kE9v1DAQxS0EoqVw4AsgH0EirR3bccwNLUuLKLBI_DlajjOmhmwcbKew8OVx2C43TvM0-r03mofQQ0pOKSH12RX0pzUnXNxCx5QoWRHG5e1Fc1YxIvkRupfSV0IIa3h9Fx3VQra1ouoY_d7EkCaw2V_DUxzN2Iet_wU9tmHMMQxDkTl6M-Aw4jkBDg7HMPlrY40fARuXIZZNF7K3OF_tYvA9TnP8AnH3DK-dK9lpMU8h5TBBNMspPBX3fXTHmSHBg5t5gj6-XH9YXVSX785frZ5fVpY1TFTQtMS2TaeoaXrS1Yr3rhOmkczJVjghesO4MLxzLVVt33ZSLZLyRhljqGUn6PE-d4rh-wwp661PFobBjBDmpKlsueSCqqagT_aoLbWkCE5P0W9N3GlK9NK1Ll3rv10X9tFN7Nxty_ZAHsotwNke-OEH2P0_SV-sXxwiq73Dpww__zlM_KbLu1Loz2_P9es3n1aCbd7rDfsD84eaIA</recordid><startdate>201604</startdate><enddate>201604</enddate><creator>Bae, Dong Sik</creator><creator>Kim, Su-jin</creator><creator>Koo, Do Hoon</creator><creator>Paek, Se-Hyun</creator><creator>Kwon, Hyungju</creator><creator>Chai, Young Jun</creator><creator>Choi, June Young</creator><creator>Lee, Kyu Eun</creator><creator>Youn, Yeo-Kyu</creator><general>Blackwell Publishing Ltd</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201604</creationdate><title>Prospective, randomized controlled trial on use of ropivacaine after robotic thyroid surgery: Effects on postoperative pain</title><author>Bae, Dong Sik ; Kim, Su-jin ; Koo, Do Hoon ; Paek, Se-Hyun ; Kwon, Hyungju ; Chai, Young Jun ; Choi, June Young ; Lee, Kyu Eun ; Youn, Yeo-Kyu</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3635-e680c86b91a6d0b294dfb5a673f785f55da345a4bf8198d8b79bf811469aaa1c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>acute pain</topic><topic>Adult</topic><topic>Amides - therapeutic use</topic><topic>Analgesics - therapeutic use</topic><topic>Anesthetics, Local - therapeutic use</topic><topic>bilateral axillo-breast approach (BABA)</topic><topic>Double-Blind Method</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Pain, Postoperative - drug therapy</topic><topic>postoperative pain</topic><topic>Prospective Studies</topic><topic>Robotic Surgical Procedures</topic><topic>robotic thyroid surgery</topic><topic>ropivacaine</topic><topic>Thyroid Gland - surgery</topic><topic>Thyroid Neoplasms - surgery</topic><topic>Thyroidectomy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bae, Dong Sik</creatorcontrib><creatorcontrib>Kim, Su-jin</creatorcontrib><creatorcontrib>Koo, Do Hoon</creatorcontrib><creatorcontrib>Paek, Se-Hyun</creatorcontrib><creatorcontrib>Kwon, Hyungju</creatorcontrib><creatorcontrib>Chai, Young Jun</creatorcontrib><creatorcontrib>Choi, June Young</creatorcontrib><creatorcontrib>Lee, Kyu Eun</creatorcontrib><creatorcontrib>Youn, Yeo-Kyu</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Head & neck</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bae, Dong Sik</au><au>Kim, Su-jin</au><au>Koo, Do Hoon</au><au>Paek, Se-Hyun</au><au>Kwon, Hyungju</au><au>Chai, Young Jun</au><au>Choi, June Young</au><au>Lee, Kyu Eun</au><au>Youn, Yeo-Kyu</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prospective, randomized controlled trial on use of ropivacaine after robotic thyroid surgery: Effects on postoperative pain</atitle><jtitle>Head & neck</jtitle><addtitle>Head Neck</addtitle><date>2016-04</date><risdate>2016</risdate><volume>38</volume><issue>S1</issue><spage>E588</spage><epage>E593</epage><pages>E588-E593</pages><issn>1043-3074</issn><eissn>1097-0347</eissn><abstract>ABSTRACT
Background
We evaluated the effects of ropivacaine for pain relief after robotic thyroid surgery.
Methods
One hundred eight patients scheduled for robotic thyroid surgery were randomized into ropivacaine (n = 54) or control (n = 54) groups. After surgery, 40 mL of 0.25% ropivacaine or 0.9% saline (control) was instilled into the skin flap. Postoperative pain intensity (visual analog scale [VAS]), analgesic requirements (fentanyl), and adverse events were assessed at 1, 2, 4, 8, 16, and 24 hours postoperatively.
Results
One hundred three patients completed the study protocol. VAS scores were lower in the ropivacaine group than the control group (p = .010); however, VAS scores were not significantly different after 8 hours postoperatively. Total analgesic consumption was higher in controls than ropivacaine‐treated patients (p = .01). Adverse events did not differ between the 2 groups.
Conclusion
Ropivacaine instillation after robotic thyroid surgery reduces acute postoperative pain and analgesic requirements without adverse events. © 2015 Wiley Periodicals, Inc. Head Neck 38: E–E, 2016</abstract><cop>United States</cop><pub>Blackwell Publishing Ltd</pub><pmid>25782919</pmid><doi>10.1002/hed.24045</doi><tpages>6</tpages></addata></record> |
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| ispartof | Head & neck, 2016-04, Vol.38 (S1), p.E588-E593 |
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| language | eng |
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| source | Wiley-Blackwell Read & Publish Collection |
| subjects | acute pain Adult Amides - therapeutic use Analgesics - therapeutic use Anesthetics, Local - therapeutic use bilateral axillo-breast approach (BABA) Double-Blind Method Female Humans Male Middle Aged Pain, Postoperative - drug therapy postoperative pain Prospective Studies Robotic Surgical Procedures robotic thyroid surgery ropivacaine Thyroid Gland - surgery Thyroid Neoplasms - surgery Thyroidectomy |
| title | Prospective, randomized controlled trial on use of ropivacaine after robotic thyroid surgery: Effects on postoperative pain |
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