Relations of vitamin D status, gender and type 2 diabetes in middle-aged Caucasians

Vitamin D (Vit D) deficiency may be linked to the development of obesity-associated complications such as insulin resistance and type 2 diabetes. We therefore evaluated the relationship of Vit D serum concentrations with metabolic parameters and type 2 diabetes in middle-aged Caucasian men and women...

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Bibliographic Details
Published in:Acta diabetologica 2015-02, Vol.52 (1), p.39-46
Main Authors: Stadlmayr, Andreas, Aigner, Elmar, Huber-Schönauer, Ursula, Niederseer, David, Zwerina, Jochen, Husar-Memmer, Emma, Hohla, Florian, Schett, Georg, Patsch, Wolfgang, Datz, Christian
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Cholecalciferol - blood
Cross-Sectional Studies
Diabetes
Diabetes Mellitus, Type 2 - blood
Diabetes Mellitus, Type 2 - diagnosis
European Continental Ancestry Group - statistics & numerical data
Female
Gender
Glycated Hemoglobin A - metabolism
Humans
Internal Medicine
Male
Medicine
Medicine & Public Health
Metabolic Diseases
Middle age
Middle Aged
Original Article
Sex Factors
Vitamin D
Vitamin deficiency
White people
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Summary:Vitamin D (Vit D) deficiency may be linked to the development of obesity-associated complications such as insulin resistance and type 2 diabetes. We therefore evaluated the relationship of Vit D serum concentrations with metabolic parameters and type 2 diabetes in middle-aged Caucasian men and women. One thousand six hundred and thirty-one Caucasians (832 males, 58.8 ± 9.7 years; 799 females, 59.7 ± 10.7 years) were evaluated in a cross-sectional study. Vit D status was assessed by measuring the serum concentration of 25-hydroxyvitamin D 3 [25(OH)D 3 ]. Type 2 diabetes prevalence was ascertained by medical history, fasting plasma glucose concentrations, oral glucose tolerance testing and/or glycosylated hemoglobin. Men displayed higher crude or seasonally adjusted 25(OH)D 3 serum concentrations than women (24.64 ± 10.98 vs. 22.88 ± 11.6 ng/ml; P  
ISSN:0940-5429
1432-5233
DOI:10.1007/s00592-014-0596-9