Pattern-Reversal Visual Evoked Potential Parameters and Migraine in the Teenage Population

• Published in: Journal of child neurology 2016-05, Vol.31 (6), p.717-721
• Main Authors: Jancic, Jasna, Petrusic, Igor, Pavlovski, Vera, Savkovic, Zorica, Vucinic, Dragana, Martinovic, Zarko
• Format: Article
• Language: English
• Subjects: Adolescent; Case-Control Studies; Chi-Square Distribution; Electroencephalography; Evoked Potentials, Visual - physiology; Female; Humans; Male; Migraine Disorders - physiopathology; Pattern Recognition, Visual - physiology; Photic Stimulation; Reaction Time - physiology; Retrospective Studies; Young Adult
• ISSN: 0883-0738; 1708-8283
• DOI: 10.1177/0883073815614399

Although migraine represents one of the most common form of primary headache in the teenage population, most neurophysiologic studies are only on the adulthood. We investigated 38 teenage patients with migraine with aura, 17 male and 21 female, with a mean age of 16.2 years, comparing them with gender- and age-matched patients with migraine without aura and healthy subjects. Also, characteristics of aura were correlated with pattern-reversal visual evoked potential parameters. There was a significant difference in left and right eye N2 wave latencies between migraine with aura and migraine without aura patients or healthy controls. In migraine with aura and migraine without aura, 26.3% of patients had abnormal wave latency. Reported tunnel vision during the aura was correlated with lower N1P1 and/or P1N2 wave amplitudes. Also, higher amplitude in patients with migraine with aura correlated with younger age and earlier disease onset, whereas longer aura duration correlated with prolonged wave latency. Findings suggest that migraine subtypes may be differentiated on the basis of N2 wave latency prolongation.