Cytogenetic monitoring of men occupationally exposed to airborne pollutants

Professional drivers had increased chromosomal aberrations that increased with duration of exposure to urban air pollution. A study of structural chromosomal aberration frequencies in peripheral blood lymphocytes was performed in a group of 20 professional drivers exposed to airborne pollutants and...

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Bibliographic Details
Published in:Environmental pollution (1987) 2001-01, Vol.112 (3), p.391-393
Main Authors: Chitra, C.K, Vishwanathan, H, Deepa, E, Usha Rani, M.V
Format: Article
Language:English
Subjects:
Adult
Air
Air Pollutants - adverse effects
Airborne pollutants
Biological and medical sciences
Chromosomal aberration
Chromosome Aberrations - blood
Chromosome Aberrations - chemically induced
Chromosome Disorders
Environmental pollutants toxicology
Humans
Lymphocytes
Lymphocytes - drug effects
Lymphocytes - ultrastructure
Male
Medical sciences
Occupational exposure
Occupational Exposure - adverse effects
Surveys and Questionnaires
Toxicology
Urban Population
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Summary:Professional drivers had increased chromosomal aberrations that increased with duration of exposure to urban air pollution. A study of structural chromosomal aberration frequencies in peripheral blood lymphocytes was performed in a group of 20 professional drivers exposed to airborne pollutants and 20 matching controls. The subjects in the latter group were of the same sex (males) and of similar age as the exposed ones, and also had similar habits of smoking and alcohol. A statistically significant increase of chromosomal aberration was observed in the exposed subjects over the control group. An increasing trend of aberrations was observed with the duration of service (exposure) in the exposed individuals. This study clearly indicates the effect of occupational exposure to airborne pollutants.
ISSN:0269-7491
1873-6424
DOI:10.1016/S0269-7491(00)00144-5