3D-Dixon cardiac magnetic resonance detects an increased epicardial fat volume in hypertensive men with myocardial infarction

Abstract Purpose Using a three-dimensional ECG- and respiratory navigator gated magnetization prepared mDixon-sequence (3D-Dixon) we quantified epi- and pericardial fat volumes (EFV, PFV) in hypertensive men compared to a healthy control group and related the amount of fat volumes in hypertensive me...

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Published in:European journal of radiology 2016-05, Vol.85 (5), p.936-942
Main Authors: Homsi, Rami, Sprinkart, Alois M, Gieseke, Juergen, Yuecel, Seyrani, Meier-Schroers, Michael, Luetkens, Julian, Dabir, Darius, Kütting, Daniel, Marx, Christian, Nadal, Jennifer, Schild, Hans H, Thomas, Daniel
Format: Article
Language:English
Subjects:
Adipose Tissue - diagnostic imaging
Adipose Tissue - pathology
CMR
Dixon
Epicardial fat
Humans
Hypertension
Hypertension - complications
Imaging, Three-Dimensional
Magnetic Resonance Imaging
Male
Middle Aged
Myocardial infarction
Myocardial Infarction - complications
Myocardial Infarction - diagnostic imaging
Myocardial Infarction - pathology
Pericardial fat
Pericardium - diagnostic imaging
Pericardium - pathology
Radiology
Risk Factors
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Summary:Abstract Purpose Using a three-dimensional ECG- and respiratory navigator gated magnetization prepared mDixon-sequence (3D-Dixon) we quantified epi- and pericardial fat volumes (EFV, PFV) in hypertensive men compared to a healthy control group and related the amount of fat volumes in hypertensive men to the presence of coronary artery disease (CAD) and myocardial infarction (MI). Materials and Methods 55 hypertensive men (mean age 63.02 ± 10.73 years [y]) with MI (n = 22; mean age 61.55 ± 10.50y) and without MI (n = 33; mean age 63.17 ± 10.93y), and a group of ten healthy men (mean age 59.00 ± 8.41y) underwent a comprehensive cardiomagnetic resonance (CMR) examination on a 1.5 Tesla MR system (Ingenia, Philips). Hypertensive men without MI consisted of patients with CAD (n = 15) and without CAD (n = 18). EFV and PFV were assessed using 3D-Dixon. Fat only images were reconstructed online at the scanner, and the segmentation of fat volumes was performed based on fat fraction maps. EFV and PFV were normalized to the body surface area (ml/m2 ). Results Mean EFV and PFV in all hypertensive men (81.8 ± 33.90 and 194.86 ± 83.51) as well as in hypertensive men with no CAD (74.53 ± 26.40 and 174.60 ± 65.70) were significantly higher than in the healthy controls (52.98 ± 19.81 and 115.50 ± 53.57; P < 0.05, each). EFV and PFV in hypertensive men with MI (94.14 ± 43.16 and 224.26 ± 100.79) were significantly higher than in hypertensive men with no MI (73.57 ± 23.27 and 175.26 ± 63.07; P
ISSN:0720-048X
1872-7727
DOI:10.1016/j.ejrad.2016.02.016