Is there a protocol in experimental skin wounds in rats using low-level diode laser therapy (LLDLT) combining or not red and infrared wavelengths? Systematic review

A systematic review addressing experiments with healing of skin wounds in rats using LLDLT with different active means seeking to identify a pattern in adjustments such as laser wavelength, power and fluency and analysing wound healing parameters, such as wound area, presence of fibroblasts, angioge...

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Bibliographic Details
Published in:Lasers in medical science 2016-05, Vol.31 (4), p.779-787
Main Authors: de Lima, Fernando José Camello, de Oliveira Neto, Olavo Barbosa, Barbosa, Fabiano Timbó, do Nascimento Galvão, Ailton Mota, Ramos, Fernando Wagner Silva, de Lima, Christiane Calheiros Farias, de Sousa Rodrigues, Célio Fernando
Format: Article
Language:English
Subjects:
Animals
Dentistry
Fibroblasts - physiology
Fibroblasts - radiation effects
Humans
Lasers
Lasers, Semiconductor - therapeutic use
Low-Level Light Therapy - methods
Medicine
Medicine & Public Health
Optical Devices
Optics
Photonics
Quantum Optics
Rats
Review Article
Skin - injuries
Skin - physiopathology
Skin - radiation effects
Wound Healing - radiation effects
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Summary:A systematic review addressing experiments with healing of skin wounds in rats using LLDLT with different active means seeking to identify a pattern in adjustments such as laser wavelength, power and fluency and analysing wound healing parameters, such as wound area, presence of fibroblasts, angiogenesis, leukocyte infiltration, epithelial coverage and antibacterial effect. It was perceived that a protocol does not exist in view of the wide variation in the use of power (9 to 500 mW) and fluency (1 to 60 J/cm2); however, between the different wavelengths, the highlight was the combined use of red and infrared wavelengths showing better results than when used alone.
ISSN:0268-8921
1435-604X
DOI:10.1007/s10103-016-1893-z