Paravalvular leak after transcatheter aortic valve implantation (TAVI): Short-term results. Data from Polish national POL-TAVI registry

The authors analyzed data from Polish national POL-TAVI registry in terms of paravalvular leak (PVL) occurrence after transcatheter aortic valve implantation (TAVI) and its impact on clinical outcomes. A total of 331 patients with severe aortic stenosis underwent TAVI (Edwards Sapien, n = 141; CoreV...

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Bibliographic Details
Published in:Cardiology journal 2016, Vol.23 (2), p.163-168
Main Authors: Kleczyński, Paweł, Zasada, Wojciech, Bagieński, Maciej, Rzeszutko, Łukasz, Sorysz, Danuta, Sobczyński, Robert, Trębacz, Jarosław, Kapelak, Bogdan, Zembala, Marian, Dudek, Dariusz
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Aortic Valve - diagnostic imaging
Aortic Valve - surgery
Aortic Valve Insufficiency - diagnosis
Aortic Valve Insufficiency - epidemiology
Aortic Valve Insufficiency - etiology
Aortic Valve Stenosis - surgery
Echocardiography, Transesophageal
Female
Follow-Up Studies
Heart Valve Prosthesis - adverse effects
Humans
Incidence
Male
Poland - epidemiology
Postoperative Complications - epidemiology
Registries
Retrospective Studies
Survival Rate - trends
Time Factors
Transcatheter Aortic Valve Replacement - adverse effects
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Summary:The authors analyzed data from Polish national POL-TAVI registry in terms of paravalvular leak (PVL) occurrence after transcatheter aortic valve implantation (TAVI) and its impact on clinical outcomes. A total of 331 patients with severe aortic stenosis underwent TAVI (Edwards Sapien, n = 141; CoreValve, n = 190). The grade of PVL and survival rate were assessed at6-month follow-up. One hundred and eighty-one (54.7%) patients developed mild PVL, and 22 (6.6%) - moderate PVL after TAVI. No severe PVLs were observed. Occurrence of moderate PVL was device dependent and more frequent in the CoreValve group (p = 0.02). Larger CoreValve device used correlated with the grade of PVL (Spearman: r = 0.19; p = 0.01), but for Edwards Sapien devices this correlation was inverted (Spearman: r = -0.62; p = 0.01). Six-month mortality rate was not significant between patients with no or mild PVL compared to those with moderate PVL (p = 0.12). The PVL occurrence remains a frequent problem after TAVI and is device de-pendent, more common with Edwards 23 mm valve and 31 mm CoreValve prosthesis.
ISSN:1897-5593
1897-5593
1898-018X
DOI:10.5603/CJ.a2015.0071