A D-optimal design to model the performances of dressings and devices for negative pressure wound therapy

Abstract A D-optimal design was used to identify and model variables that affect the transit time of wound exudate through an illustrative dressing used for negative pressure wound therapy. Many authors have addressed the clinical benefits of negative pressure wound therapy, but limited information...

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Bibliographic Details
Published in:Journal of tissue viability 2016-05, Vol.25 (2), p.83-90
Main Authors: Salvo, P, Smajda, R, Dini, V, Saxby, C, Voirin, G, Romanelli, M, Di Francesco, F
Format: Article
Language:English
Subjects:
Advanced Basic Science
Bandages
Chronic wounds
Critical Care
D-optimal design
Exudate transit time
Exudates and Transudates - physiology
Models, Theoretical
Negative pressure wound therapy
Negative-Pressure Wound Therapy - instrumentation
Negative-Pressure Wound Therapy - methods
Nursing
Wound dressing
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Summary:Abstract A D-optimal design was used to identify and model variables that affect the transit time of wound exudate through an illustrative dressing used for negative pressure wound therapy. Many authors have addressed the clinical benefits of negative pressure wound therapy, but limited information is available on how to assess performances of dressings. In this paper, the transit time of wound exudate through a dressing was chosen as a model parameter to show how experimental design (DOE) can be used for this purpose. Results demonstrated that rate of exudate production, temperature and dressing thickness were the variables with the largest impact on transit time. The DOE approach could be used to model other dressing properties, like for example capability of absorbing excess exudate or breathability.
ISSN:0965-206X
DOI:10.1016/j.jtv.2016.01.001