Metal implant sensitivity: clinical and histological presentation

Metal implant sensitivity (intolerance) can cause pain, reduced mobility, loosening of the implant and skin rashes. Knowledge of differential diagnoses, histology and appropriate diagnostics are essential for proper diagnosis. To outline typical clinical signs and histology in metal-implant-associat...

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Bibliographic Details
Published in:Hautarzt 2016-05, Vol.67 (5), p.373-379
Main Authors: Hartmann, D, Letulé, V, Schneider, J J, Flaig, M J
Format: Article
Language:ger
Subjects:
Dermatitis, Contact - etiology
Dermatitis, Contact - immunology
Dermatitis, Contact - pathology
Diagnosis, Differential
Disorders of Excessive Somnolence - etiology
Disorders of Excessive Somnolence - immunology
Disorders of Excessive Somnolence - pathology
Humans
Metals - adverse effects
Prostheses and Implants - adverse effects
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Summary:Metal implant sensitivity (intolerance) can cause pain, reduced mobility, loosening of the implant and skin rashes. Knowledge of differential diagnoses, histology and appropriate diagnostics are essential for proper diagnosis. To outline typical clinical signs and histology in metal-implant-associated skin lesions we present three exemplary patients from our implant allergy outpatient department and give an overview of the current literature regarding metal implant sensitivity. In patients with a negative patch test the lymphocyte transformation test may reveal metal sensitization. Even "pure" titanium alloys may contain traces of nickel. The histology of implant-associated skin reactions goes from teleangiectatic postimplantation erythema to eczema and vasculitis. Based on the synopsis of history, clinical picture, allergological testing and histology, metal implant sensitivity can be diagnosed more precisely.
ISSN:1432-1173
DOI:10.1007/s00105-016-3790-6