Cervical Vertebral Body Chordoma in a Cat

A 9-year-old, neutered female Maine Coon cat with a 6-week history of progressive ataxia was diagnosed with a cervical vertebral body mass using magnetic resonance imaging. The mass displaced and compressed the cervical spinal cord. The cat was humanely destroyed and necropsy examination confirmed a...

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Bibliographic Details
Published in:Journal of comparative pathology 2016-05, Vol.154 (4), p.319-322
Main Authors: Hampel, R., Taylor-Brown, F., Priestnall, S.L.
Format: Article
Language:English
Subjects:
Animals
Biomarkers, Tumor - analysis
cat
Cat Diseases - pathology
Cats
Cervical Vertebrae
chordoma
Chordoma - veterinary
Female
Immunohistochemistry
Spinal Neoplasms - veterinary
vertebral body
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Summary:A 9-year-old, neutered female Maine Coon cat with a 6-week history of progressive ataxia was diagnosed with a cervical vertebral body mass using magnetic resonance imaging. The mass displaced and compressed the cervical spinal cord. The cat was humanely destroyed and necropsy examination confirmed a mass within the second cervical vertebral body. Microscopically, the mass was composed of large, clear, vacuolated (‘physaliferous’) cells. Immunohistochemically, the neoplastic cells expressed both cytokeratin and vimentin and the final diagnosis was a cervical, vertebral body chordoma. This is only the third report of a chordoma in this species and the first in this location. Chordoma should be considered as a potential differential diagnosis for tumours arising from the cervical vertebrae in the cat.
ISSN:0021-9975
1532-3129
DOI:10.1016/j.jcpa.2016.03.006