The utility of indocyanine green near infrared fluorescent imaging in the identification of parathyroid glands during surgery for primary hyperparathyroidism

Background and Objectives Intraoperative adjuncts for the localization of parathyroid glands in parathyroid surgery are limited. The aim of this study is to assess the usefulness of indocyanine green (ICG) near‐infrared (NIR) fluorescent imaging in patients undergoing surgery for primary hyperparath...

Full description

Saved in:
Bibliographic Details
Published in:Journal of surgical oncology 2016-06, Vol.113 (7), p.771-774
Main Authors: Zaidi, Nisar, Bucak, Emre, Okoh, Alexis, Yazici, Pinar, Yigitbas, Hakan, Berber, Eren
Format: Article
Language:English
Subjects:
Adult
Female
fluorescence-guided surgery
Fluorescent Dyes
Humans
hyperparathyroidism
Hyperparathyroidism, Primary - diagnostic imaging
Hyperparathyroidism, Primary - surgery
Indocyanine Green
Male
Middle Aged
near-infrared fluorescence
Optical Imaging - methods
Parathyroid Glands - diagnostic imaging
Parathyroid Glands - surgery
parathyroidectomy
Parathyroidectomy - methods
Prospective Studies
Spectroscopy, Near-Infrared
Thyroid Gland - diagnostic imaging
Treatment Outcome
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background and Objectives Intraoperative adjuncts for the localization of parathyroid glands in parathyroid surgery are limited. The aim of this study is to assess the usefulness of indocyanine green (ICG) near‐infrared (NIR) fluorescent imaging in patients undergoing surgery for primary hyperparathyroidism (PHPT). Methods ICG imaging was performed in 33 patients undergoing parathyroidectomy (PTX). Thyroid and parathyroid ICG uptake were assessed and independently verified on a grading scale. Clinical variables were recorded and analyzed for factors associated with ICG uptake. Results Of 112 glands identified by naked eye, 104 (92.9%) demonstrated ICG uptake. Concomitant ICG fluorescence was identified in the thyroid in all patients. There was a trend toward increased ICG fluorescence in patients 11 mg/dl (P = 0.04) and in those parathyroids larger than 10 mm (P 
ISSN:0022-4790
1096-9098
DOI:10.1002/jso.24240