Inhaled corticosteroids: Which regimens are appropriate?

Inhaled corticosteroids are the cornerstone of asthma management. Inhaled corticosteroid regimens differ slightly in various international guidelines on asthma management but are based on the principles of continuous treatment and titration to the lowest effective dose. Several recent studies, never...

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Bibliographic Details
Published in:Archives de pédiatrie : organe officiel de la Société française de pédiatrie 2016-06, Vol.23 (6), p.658-663
Main Authors: Giovannini-Chami, L, Piccini-Bailly, C, Albertini, M
Format: Article
Language:fre
Subjects:
Administration, Inhalation
Asthma - drug therapy
Child, Preschool
Dose-Response Relationship, Drug
Glucocorticoids - administration & dosage
Glucocorticoids - therapeutic use
Humans
Infant
Nebulizers and Vaporizers
Practice Guidelines as Topic
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Summary:Inhaled corticosteroids are the cornerstone of asthma management. Inhaled corticosteroid regimens differ slightly in various international guidelines on asthma management but are based on the principles of continuous treatment and titration to the lowest effective dose. Several recent studies, nevertheless, appear to demonstrate the potential value of preemptive or "pro re nata" regimens in infants and children. These studies were included in GINA 2015 for children 5 years of age and younger in whom discontinuous treatment is proposed as a second-line option. Should we change our practices after a critical reading of these studies?
ISSN:1769-664X
DOI:10.1016/j.arcped.2016.03.019