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Efficacy, safety, and acceptability of thermocoagulation for treatment of cervical intraepithelial neoplasia in a hospital setting in Brazil

Abstract Objective To analyze the acceptability, safety, and effectiveness of thermocoagulation for the treatment of histologically proven cervical intraepithelial neoplasia grade 2–3 (CIN2–3) lesions. Methods In a retrospective study, data were obtained for women treated for CIN2–3 lesions by therm...

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Published in:International journal of gynecology and obstetrics 2016-06, Vol.133 (3), p.351-354
Main Authors: Naud, Paulo S.V, Muwonge, Richard, Passos, Eduardo P, Magno, Valentino, Matos, Jean, Sankaranarayanan, Rengaswamy
Format: Article
Language:English
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Summary:Abstract Objective To analyze the acceptability, safety, and effectiveness of thermocoagulation for the treatment of histologically proven cervical intraepithelial neoplasia grade 2–3 (CIN2–3) lesions. Methods In a retrospective study, data were obtained for women treated for CIN2–3 lesions by thermocoagulation at the Hospital de Clínicas de Porto Alegre, Brazil, between March 6, 2012, and October 29, 2013, and followed up after 1 year. The proportions of women with no evidence of disease, adverse effects, or complications were determined. Results Among 52 women included, 44 (85%) had no evidence of disease 1 year after thermocoagulation. The rate of no disease at follow-up was similar for women treated for CIN2 (17/20 [85%]) and CIN3 (27/32 [84%]). No serious adverse effects or complications requiring hospitalization were observed during the follow-up period. Conclusion Thermocoagulation is useful in the management of ectocervical CIN and should be integrated into public health services for management of cervical cancer.
ISSN:0020-7292
1879-3479
DOI:10.1016/j.ijgo.2015.09.035