Different risk factors for candidemia occur for Candida species belonging to the C. parapsilosis complex

Previous studies have demonstrated reduced virulence in the species that comprise the Candida parapsilosis complex. We investigated a cohort of 93 patients with candidemia caused by this complex. Most infections were caused by C. parapsilosis (80.6%), followed by C. orthopsilosis (18.3%) and C. meta...

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Bibliographic Details
Published in:Medical mycology (Oxford) 2014-05, Vol.52 (4), p.403-406
Main Authors: Constante, C. C., Monteiro, A. A., Alves, S. H., Carneiro, L. C., Machado, M. M., Severo, L. C., Park, S., Perlin, D. S., Pasqualotto, A. C.
Format: Article
Language:English
Subjects:
Candida
Candida - classification
Candida - isolation & purification
Candida parapsilosis
Candidemia - complications
Candidemia - epidemiology
Candidemia - microbiology
Cohort Studies
Humans
Liver Diseases - epidemiology
Liver Diseases - etiology
Prevalence
Renal Insufficiency - epidemiology
Renal Insufficiency - etiology
Risk Assessment
Risk Factors
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Summary:Previous studies have demonstrated reduced virulence in the species that comprise the Candida parapsilosis complex. We investigated a cohort of 93 patients with candidemia caused by this complex. Most infections were caused by C. parapsilosis (80.6%), followed by C. orthopsilosis (18.3%) and C. metapsilosis (1.1%). Renal failure (P < 0.001) and chronic liver diseases (P = 0.019) were more frequently encountered with infections caused by the C. orthopsilosis group, suggesting an association with patients who had a greater state of immune suppression in comparison with infections caused by C. parapsilosis sensu stricto.
ISSN:1369-3786
1460-2709
DOI:10.1093/mmy/myt034