Altered metabolic parameters in association with antipsychotic medication use in diabetes: A population based case-control study

Highlights • This study confirms higher diabetes rates in the schizophrenia population up to age 70 but not beyond, suggesting a survivor effect. • This study utilises a national linked diabetes dataset to assess associations between antipsychotic use and diabetes parameters/outcomes. • This study i...

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Bibliographic Details
Published in:Psychoneuroendocrinology 2016-04, Vol.66, p.214-220
Main Authors: Wake, D.J, Broughton, P, Perera, S.M, MacIntyre, D.J, Leese, G.P
Format: Article
Language:English
Subjects:
Adult
Aged
Antipsychotic Agents - therapeutic use
Antipsychotics
Bipolar Disorder - drug therapy
Bipolar Disorder - epidemiology
Case-control
Case-Control Studies
Diabetes
Diabetes Complications - epidemiology
Diabetes Complications - metabolism
Diabetes Complications - psychology
Diabetes Mellitus - epidemiology
Endocrinology & Metabolism
Female
Humans
Male
Mental health
Metabolic
Metabolic Diseases - epidemiology
Middle Aged
Prevalence
Psychiatry
Risk Factors
Schizophrenia
Schizophrenia - drug therapy
Schizophrenia - epidemiology
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Summary:Highlights • This study confirms higher diabetes rates in the schizophrenia population up to age 70 but not beyond, suggesting a survivor effect. • This study utilises a national linked diabetes dataset to assess associations between antipsychotic use and diabetes parameters/outcomes. • This study is novel, demonstrating slight improved diabetes-related parameters/outcomes in patients prescribed antipsychotics vs controls.
ISSN:0306-4530
1873-3360
DOI:10.1016/j.psyneuen.2016.01.022