Optic Nerve Assessment Using 7-Tesla Magnetic Resonance Imaging

PURPOSEThe purpose of this study was to correlate high-resolution magnetic resonance imaging (MRI) and histologic findings in a case of juxtapapillary choroidal melanoma with clinical evidence of optic nerve invasion. METHODSWith institutional review board approval, an enucleated globe with choroida...

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Bibliographic Details
Published in:Ocular oncology and pathology 2016, Vol.2 (3), p.178-180
Main Authors: Singh, Arun D, Platt, Sean M, Lystad, Lisa, Lowe, Mark, Oh, Sehong, Jones, Stephen E, Alzahrani, Yahya, Plesec, Thomas
Format: Report
Language:English
Online Access:Get full text
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Summary:PURPOSEThe purpose of this study was to correlate high-resolution magnetic resonance imaging (MRI) and histologic findings in a case of juxtapapillary choroidal melanoma with clinical evidence of optic nerve invasion. METHODSWith institutional review board approval, an enucleated globe with choroidal melanoma and optic nerve invasion was imaged using a 7-tesla MRI followed by histopathologic evaluation. RESULTSOptical coherence tomography, B-scan ultrasonography, and 1.5-tesla MRI of the orbit (1-mm sections) could not detect optic disc invasion. Ex vivo, 7-tesla MRI detected optic nerve invasion, which correlated with histopathologic features. CONCLUSIONSOur case demonstrates the potential to document the existence of optic nerve invasion in the presence of an intraocular tumor, a feature that has a major bearing on decision making, particularly for consideration of enucleation.
ISSN:2296-4681
DOI:10.1159/000443650