Adenocarcinoma of the Rectum—A Composite of Three Different Subtypes With Varying Outcomes?

Micro-Abstract We conducted a retrospective database analysis of patients with rectal cancer at a tertiary cancer referral center in Western India, with a special focus on the effect of histologic subtype on cancer outcomes. We found that a spectrum of adenocarcinoma subtypes exists, with patients w...

Full description

Saved in:
Bibliographic Details
Published in:Clinical colorectal cancer 2016-06, Vol.15 (2), p.e47-e52
Main Authors: Vallam, Karthik Chandra, Desouza, Ashwin, Bal, Munita, Patil, Prachi, Engineer, Reena, Saklani, Avanish
Format: Article
Language:English
Subjects:
Adenocarcinoma - mortality
Adenocarcinoma - pathology
Adenocarcinoma - therapy
Adult
Aged
Chemoradiotherapy, Adjuvant
Combined Modality Therapy
Digestive System Surgical Procedures
Disease-Free Survival
Female
Gastroenterology and Hepatology
Hematology, Oncology and Palliative Medicine
Histopathological subtypes
Humans
Kaplan-Meier Estimate
Male
Middle Aged
Mucinous adenocarcinoma
Neoadjuvant Therapy - methods
Prognosis
Rectal cancer
Rectal Neoplasms - mortality
Rectal Neoplasms - pathology
Rectal Neoplasms - therapy
Retrospective Studies
Signet ring cell carcinoma
Survival outcomes
Treatment Outcome
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c411t-2d0cd317f6bfaf4a036f4c5ac01ba2621fab1dd73b3186fad4205b1ef3b834783
cites cdi_FETCH-LOGICAL-c411t-2d0cd317f6bfaf4a036f4c5ac01ba2621fab1dd73b3186fad4205b1ef3b834783
container_end_page e52
container_issue 2
container_start_page e47
container_title Clinical colorectal cancer
container_volume 15
creator Vallam, Karthik Chandra
Desouza, Ashwin
Bal, Munita
Patil, Prachi
Engineer, Reena
Saklani, Avanish
description Micro-Abstract We conducted a retrospective database analysis of patients with rectal cancer at a tertiary cancer referral center in Western India, with a special focus on the effect of histologic subtype on cancer outcomes. We found that a spectrum of adenocarcinoma subtypes exists, with patients with mucinous variants exhibiting clinicopathologic outcomes intermediate between that of the classic and signet ring cell variants.
doi_str_mv 10.1016/j.clcc.2015.12.004
format article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1792775026</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>1_s2_0_S1533002815001553</els_id><sourcerecordid>1792775026</sourcerecordid><originalsourceid>FETCH-LOGICAL-c411t-2d0cd317f6bfaf4a036f4c5ac01ba2621fab1dd73b3186fad4205b1ef3b834783</originalsourceid><addsrcrecordid>eNp9kc9u1DAQxi0EomXhBTigHLkk9dhJnEoItFr-SpUq0QInZDn2mPWSxFvbQdobD8ET8iR1tIUDB04ea77v08xvCHkKtAIK7dmu0oPWFaPQVMAqSut75BTOeVfSVtT3c91wXlLKuhPyKMZdrloO8JCcsFaIrq2bU_J1bXDyWgXtJj-qwtsibbH4iDrN4--fv9bFxo97H13CpXe9DYjFa2ctBpxScTX36bDHWHxxaVt8VuHgpm_F5Zy0HzG-ekweWDVEfHL3rsint2-uN-_Li8t3Hzbri1LXAKlkhmrDQdi2t8rWivLW1rpRmkKvWMvAqh6MEbzn0LVWmZrRpge0vO94LTq-Is-Pufvgb2aMSY4uahwGNaGfowRxzoRolv1XhB2lOvgYA1q5D27Mg0ugcsEqd3LBKhesEpjMWLPp2V3-3I9o_lr-cMyCF0cB5i1_OAwyaoeTRuNCRimNd__Pf_mPXQ9ucloN3_GAcefnMGV-EmTMBnm1HHa5KzQ0p-TPLXOKnuY</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1792775026</pqid></control><display><type>article</type><title>Adenocarcinoma of the Rectum—A Composite of Three Different Subtypes With Varying Outcomes?</title><source>Elsevier</source><creator>Vallam, Karthik Chandra ; Desouza, Ashwin ; Bal, Munita ; Patil, Prachi ; Engineer, Reena ; Saklani, Avanish</creator><creatorcontrib>Vallam, Karthik Chandra ; Desouza, Ashwin ; Bal, Munita ; Patil, Prachi ; Engineer, Reena ; Saklani, Avanish</creatorcontrib><description>Micro-Abstract We conducted a retrospective database analysis of patients with rectal cancer at a tertiary cancer referral center in Western India, with a special focus on the effect of histologic subtype on cancer outcomes. We found that a spectrum of adenocarcinoma subtypes exists, with patients with mucinous variants exhibiting clinicopathologic outcomes intermediate between that of the classic and signet ring cell variants.</description><identifier>ISSN: 1533-0028</identifier><identifier>EISSN: 1938-0674</identifier><identifier>DOI: 10.1016/j.clcc.2015.12.004</identifier><identifier>PMID: 26778645</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adenocarcinoma - mortality ; Adenocarcinoma - pathology ; Adenocarcinoma - therapy ; Adult ; Aged ; Chemoradiotherapy, Adjuvant ; Combined Modality Therapy ; Digestive System Surgical Procedures ; Disease-Free Survival ; Female ; Gastroenterology and Hepatology ; Hematology, Oncology and Palliative Medicine ; Histopathological subtypes ; Humans ; Kaplan-Meier Estimate ; Male ; Middle Aged ; Mucinous adenocarcinoma ; Neoadjuvant Therapy - methods ; Prognosis ; Rectal cancer ; Rectal Neoplasms - mortality ; Rectal Neoplasms - pathology ; Rectal Neoplasms - therapy ; Retrospective Studies ; Signet ring cell carcinoma ; Survival outcomes ; Treatment Outcome</subject><ispartof>Clinical colorectal cancer, 2016-06, Vol.15 (2), p.e47-e52</ispartof><rights>Elsevier Inc.</rights><rights>2015 Elsevier Inc.</rights><rights>Copyright © 2015 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c411t-2d0cd317f6bfaf4a036f4c5ac01ba2621fab1dd73b3186fad4205b1ef3b834783</citedby><cites>FETCH-LOGICAL-c411t-2d0cd317f6bfaf4a036f4c5ac01ba2621fab1dd73b3186fad4205b1ef3b834783</cites><orcidid>0000-0002-3356-6145</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26778645$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Vallam, Karthik Chandra</creatorcontrib><creatorcontrib>Desouza, Ashwin</creatorcontrib><creatorcontrib>Bal, Munita</creatorcontrib><creatorcontrib>Patil, Prachi</creatorcontrib><creatorcontrib>Engineer, Reena</creatorcontrib><creatorcontrib>Saklani, Avanish</creatorcontrib><title>Adenocarcinoma of the Rectum—A Composite of Three Different Subtypes With Varying Outcomes?</title><title>Clinical colorectal cancer</title><addtitle>Clin Colorectal Cancer</addtitle><description>Micro-Abstract We conducted a retrospective database analysis of patients with rectal cancer at a tertiary cancer referral center in Western India, with a special focus on the effect of histologic subtype on cancer outcomes. We found that a spectrum of adenocarcinoma subtypes exists, with patients with mucinous variants exhibiting clinicopathologic outcomes intermediate between that of the classic and signet ring cell variants.</description><subject>Adenocarcinoma - mortality</subject><subject>Adenocarcinoma - pathology</subject><subject>Adenocarcinoma - therapy</subject><subject>Adult</subject><subject>Aged</subject><subject>Chemoradiotherapy, Adjuvant</subject><subject>Combined Modality Therapy</subject><subject>Digestive System Surgical Procedures</subject><subject>Disease-Free Survival</subject><subject>Female</subject><subject>Gastroenterology and Hepatology</subject><subject>Hematology, Oncology and Palliative Medicine</subject><subject>Histopathological subtypes</subject><subject>Humans</subject><subject>Kaplan-Meier Estimate</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Mucinous adenocarcinoma</subject><subject>Neoadjuvant Therapy - methods</subject><subject>Prognosis</subject><subject>Rectal cancer</subject><subject>Rectal Neoplasms - mortality</subject><subject>Rectal Neoplasms - pathology</subject><subject>Rectal Neoplasms - therapy</subject><subject>Retrospective Studies</subject><subject>Signet ring cell carcinoma</subject><subject>Survival outcomes</subject><subject>Treatment Outcome</subject><issn>1533-0028</issn><issn>1938-0674</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><recordid>eNp9kc9u1DAQxi0EomXhBTigHLkk9dhJnEoItFr-SpUq0QInZDn2mPWSxFvbQdobD8ET8iR1tIUDB04ea77v08xvCHkKtAIK7dmu0oPWFaPQVMAqSut75BTOeVfSVtT3c91wXlLKuhPyKMZdrloO8JCcsFaIrq2bU_J1bXDyWgXtJj-qwtsibbH4iDrN4--fv9bFxo97H13CpXe9DYjFa2ctBpxScTX36bDHWHxxaVt8VuHgpm_F5Zy0HzG-ekweWDVEfHL3rsint2-uN-_Li8t3Hzbri1LXAKlkhmrDQdi2t8rWivLW1rpRmkKvWMvAqh6MEbzn0LVWmZrRpge0vO94LTq-Is-Pufvgb2aMSY4uahwGNaGfowRxzoRolv1XhB2lOvgYA1q5D27Mg0ugcsEqd3LBKhesEpjMWLPp2V3-3I9o_lr-cMyCF0cB5i1_OAwyaoeTRuNCRimNd__Pf_mPXQ9ucloN3_GAcefnMGV-EmTMBnm1HHa5KzQ0p-TPLXOKnuY</recordid><startdate>20160601</startdate><enddate>20160601</enddate><creator>Vallam, Karthik Chandra</creator><creator>Desouza, Ashwin</creator><creator>Bal, Munita</creator><creator>Patil, Prachi</creator><creator>Engineer, Reena</creator><creator>Saklani, Avanish</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-3356-6145</orcidid></search><sort><creationdate>20160601</creationdate><title>Adenocarcinoma of the Rectum—A Composite of Three Different Subtypes With Varying Outcomes?</title><author>Vallam, Karthik Chandra ; Desouza, Ashwin ; Bal, Munita ; Patil, Prachi ; Engineer, Reena ; Saklani, Avanish</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c411t-2d0cd317f6bfaf4a036f4c5ac01ba2621fab1dd73b3186fad4205b1ef3b834783</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Adenocarcinoma - mortality</topic><topic>Adenocarcinoma - pathology</topic><topic>Adenocarcinoma - therapy</topic><topic>Adult</topic><topic>Aged</topic><topic>Chemoradiotherapy, Adjuvant</topic><topic>Combined Modality Therapy</topic><topic>Digestive System Surgical Procedures</topic><topic>Disease-Free Survival</topic><topic>Female</topic><topic>Gastroenterology and Hepatology</topic><topic>Hematology, Oncology and Palliative Medicine</topic><topic>Histopathological subtypes</topic><topic>Humans</topic><topic>Kaplan-Meier Estimate</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Mucinous adenocarcinoma</topic><topic>Neoadjuvant Therapy - methods</topic><topic>Prognosis</topic><topic>Rectal cancer</topic><topic>Rectal Neoplasms - mortality</topic><topic>Rectal Neoplasms - pathology</topic><topic>Rectal Neoplasms - therapy</topic><topic>Retrospective Studies</topic><topic>Signet ring cell carcinoma</topic><topic>Survival outcomes</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Vallam, Karthik Chandra</creatorcontrib><creatorcontrib>Desouza, Ashwin</creatorcontrib><creatorcontrib>Bal, Munita</creatorcontrib><creatorcontrib>Patil, Prachi</creatorcontrib><creatorcontrib>Engineer, Reena</creatorcontrib><creatorcontrib>Saklani, Avanish</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical colorectal cancer</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Vallam, Karthik Chandra</au><au>Desouza, Ashwin</au><au>Bal, Munita</au><au>Patil, Prachi</au><au>Engineer, Reena</au><au>Saklani, Avanish</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Adenocarcinoma of the Rectum—A Composite of Three Different Subtypes With Varying Outcomes?</atitle><jtitle>Clinical colorectal cancer</jtitle><addtitle>Clin Colorectal Cancer</addtitle><date>2016-06-01</date><risdate>2016</risdate><volume>15</volume><issue>2</issue><spage>e47</spage><epage>e52</epage><pages>e47-e52</pages><issn>1533-0028</issn><eissn>1938-0674</eissn><abstract>Micro-Abstract We conducted a retrospective database analysis of patients with rectal cancer at a tertiary cancer referral center in Western India, with a special focus on the effect of histologic subtype on cancer outcomes. We found that a spectrum of adenocarcinoma subtypes exists, with patients with mucinous variants exhibiting clinicopathologic outcomes intermediate between that of the classic and signet ring cell variants.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>26778645</pmid><doi>10.1016/j.clcc.2015.12.004</doi><orcidid>https://orcid.org/0000-0002-3356-6145</orcidid></addata></record>
fulltext fulltext
identifier ISSN: 1533-0028
ispartof Clinical colorectal cancer, 2016-06, Vol.15 (2), p.e47-e52
issn 1533-0028
1938-0674
language eng
recordid cdi_proquest_miscellaneous_1792775026
source Elsevier
subjects Adenocarcinoma - mortality
Adenocarcinoma - pathology
Adenocarcinoma - therapy
Adult
Aged
Chemoradiotherapy, Adjuvant
Combined Modality Therapy
Digestive System Surgical Procedures
Disease-Free Survival
Female
Gastroenterology and Hepatology
Hematology, Oncology and Palliative Medicine
Histopathological subtypes
Humans
Kaplan-Meier Estimate
Male
Middle Aged
Mucinous adenocarcinoma
Neoadjuvant Therapy - methods
Prognosis
Rectal cancer
Rectal Neoplasms - mortality
Rectal Neoplasms - pathology
Rectal Neoplasms - therapy
Retrospective Studies
Signet ring cell carcinoma
Survival outcomes
Treatment Outcome
title Adenocarcinoma of the Rectum—A Composite of Three Different Subtypes With Varying Outcomes?
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-04T08%3A24%3A36IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Adenocarcinoma%20of%20the%20Rectum%E2%80%94A%20Composite%20of%20Three%20Different%20Subtypes%20With%20Varying%20Outcomes?&rft.jtitle=Clinical%20colorectal%20cancer&rft.au=Vallam,%20Karthik%20Chandra&rft.date=2016-06-01&rft.volume=15&rft.issue=2&rft.spage=e47&rft.epage=e52&rft.pages=e47-e52&rft.issn=1533-0028&rft.eissn=1938-0674&rft_id=info:doi/10.1016/j.clcc.2015.12.004&rft_dat=%3Cproquest_cross%3E1792775026%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c411t-2d0cd317f6bfaf4a036f4c5ac01ba2621fab1dd73b3186fad4205b1ef3b834783%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1792775026&rft_id=info:pmid/26778645&rfr_iscdi=true