Sarcopenia Evaluated Using the Skeletal Muscle Index Is a Significant Prognostic Factor for Metastatic Urothelial Carcinoma

Micro-Abstract The prognostic significance of sarcopenia (muscle loss) in patients with metastatic urothelial carcinoma (UC) is unclear. Furthermore, its evaluation methods are not entirely standardized. Using several types of computed tomography-based evaluation, we assessed the association of sarc...

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Published in:Clinical genitourinary cancer 2016-06, Vol.14 (3), p.237-243
Main Authors: Taguchi, Satoru, Akamatsu, Nobuhiko, Nakagawa, Tohru, Gonoi, Wataru, Kanatani, Atsushi, Miyazaki, Hideyo, Fujimura, Tetsuya, Fukuhara, Hiroshi, Kume, Haruki, Homma, Yukio
Format: Article
Language:English
Subjects:
Aged
Biomarker
Bladder cancer
Carcinoma, Transitional Cell - diagnosis
Carcinoma, Transitional Cell - mortality
Carcinoma, Transitional Cell - secondary
Chemotherapy
Computed tomography
Female
Hematology, Oncology and Palliative Medicine
Humans
Kaplan-Meier Estimate
Lymphatic Metastasis
Male
Middle Aged
Multivariate Analysis
Muscle, Skeletal - pathology
Prognosis
Retrospective Studies
Sarcopenia - diagnosis
Sarcopenia - mortality
Urinary Bladder Neoplasms - diagnosis
Urinary Bladder Neoplasms - mortality
Urinary Bladder Neoplasms - pathology
Urology
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Summary:Micro-Abstract The prognostic significance of sarcopenia (muscle loss) in patients with metastatic urothelial carcinoma (UC) is unclear. Furthermore, its evaluation methods are not entirely standardized. Using several types of computed tomography-based evaluation, we assessed the association of sarcopenia with survival in patients with metastatic UC. Multivariate analysis showed that sarcopenia was an independent prognostic factor in an evaluation using skeletal muscle index.
ISSN:1558-7673
1938-0682
DOI:10.1016/j.clgc.2015.07.015