Primary Cardiac Osteosarcoma

Background Primary cardiac osteosarcoma is extremely rare. There is no cohort study on such tumours to date. The aim of this study is to investigate the clinical characteristics and outcome patterns of such tumours. Methods A thorough literature review was performed, and all relevant clinical items...

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Bibliographic Details
Published in:Heart, lung & circulation lung & circulation, 2016-07, Vol.25 (7), p.698-704
Main Authors: Wang, Ji-Gang, MD, PhD, Liu, Bing, MD, Gao, Han, MD, Li, Yu-Jun, MD, Zhao, Peng, MD, Liu, Xiu-Ping, MD, PhD
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Bone Neoplasms - epidemiology
Bone Neoplasms - pathology
Cardiac tumour
Cardiovascular
Female
Heart Neoplasms - epidemiology
Heart Neoplasms - pathology
Humans
Male
Middle Aged
Osteosarcoma
Osteosarcoma - epidemiology
Osteosarcoma - pathology
Prognosis
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Summary:Background Primary cardiac osteosarcoma is extremely rare. There is no cohort study on such tumours to date. The aim of this study is to investigate the clinical characteristics and outcome patterns of such tumours. Methods A thorough literature review was performed, and all relevant clinical items were collected. A total of 53 cases of primary cardiac osteosarcoma were enrolled in this study, including 25 males and 28 females. Results The age at diagnosis ranged from 14 to 77 years with a mean age of 43.6 years. The clinical manifestations, imaging features, and laboratory tests of the primary cardiac osteosarcomas were similar to other types of primary cardiac tumours. Sex, tumour size and adjunctive chemo-radiotherapy were found to affect the overall survival pattern. Conclusions The present study may provide an effective consultation for the diagnosis and treatment of this tumour.
ISSN:1443-9506
1444-2892
DOI:10.1016/j.hlc.2016.01.006