Facile synthesis of hexagonal-shaped polypyrrole self-assembled particles for the electrochemical detection of dopamine

• Published in: Applied surface science 2016-02, Vol.363, p.451-458
• Main Authors: Lee, Chung-Yi, Hsu, Di-Yao, Prasannan, Adhimoorthy, Kalaivani, Raman, Hong, Po-Da
• Format: Article
• Language: English
• Subjects: Biosensors; Dopamine; Dopamine sensor; Electrochemical analysis; Electrodes; Inclusion complex; Neurotransmitters; Polymerization; Polypyrrole; Polypyrroles; Self-assembly; Synthesis; β-cyclodextrin
• ISSN: 0169-4332; 1873-5584
• DOI: 10.1016/j.apsusc.2015.12.138

•Facile synthesis of the hexagonal-shaped plates-like polypyrrole was prepared to detect the neurotransmitter dopamine.•Host–guest pyrrole-β-CD complex was used as monomer to polymerization.•Well-defined hexagonal shaped PPY-IC obtained via intermolecular interactions such as π–π interactions and hydrogen bonding between β-CD and PPY.•PPY-IC modified glassy carbon electrode has been used for the electrochemical detection of dopamine. Nanomaterials have been used as an electroactive medium to enhance the efficiency of bio/chemical sensors, primarily when synergy is reached upon mixing different materials. In this study, we report on the facile synthesis of hexagonal-shaped plate-like polypyrrole (PPY-IC) prepared through inclusion polymerization of the host–guest pyrrole monomeric inclusion complex of β-cyclodextrin (β-CD) to be used in the detection of the neurotransmitter dopamine (DA). The amount of the monomer complex plays a crucial role in the fabrication of well-defined hexagonal-shaped PPY-IC through intermolecular interactions such as π–π interactions and hydrogen bonding between the β-CD and PPY. The microstructure and morphology of the PPY-IC were examined by using various analytical techniques and a tentative mechanism for the growth process proposed which elucidates the formation of the hierarchical structure of the PPY-IC. Cyclo-voltammetry was performed with a PPY-IC modified glassy carbon electrode (GCE) for the electrochemical detection of DA. The concepts behind the novel architecture of the PPY-IC modified electrodes have potential for the production of materials to be used in electrochemical sensors and biosensors.