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Tetraphenylethene End-capped Polyethylenimine Fluorescent Nanoparticles for Cell Imaging

Water soluble tetraphenylethene-based(TPE) aggregation-induced emission fluorescent organic nanoparticles(FONs) were facilely prepared via Schiff base condensation with polyethylenimine(PEI) and subsequent reduction. The obtained TPE-PEI FONs were characterized by a series of techniques including 1H...

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Bibliographic Details
Published in:Chinese journal of polymer science 2014-11, Vol.32 (11), p.1479-1488
Main Authors: Zhang, Xi-qi, Zhang, Xiao-yong, Yang, Bin, Wei, Yen
Format: Article
Language:English
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Summary:Water soluble tetraphenylethene-based(TPE) aggregation-induced emission fluorescent organic nanoparticles(FONs) were facilely prepared via Schiff base condensation with polyethylenimine(PEI) and subsequent reduction. The obtained TPE-PEI FONs were characterized by a series of techniques including 1H-NMR, 13C-NMR, gel permeation chromatography, UV absorption spectra, fluorescence spectra, Fourier transform infrared spectroscopy, size distribution and zeta potential measurement, and transmission electron microscopy. Biocompatibility evaluation and cell imaging of TPE-PEI FONs were further explored. We demonstrated that such FONs showed intense fluorescence, spherical morphology and excellent biocompatibility, making them very suitable for cell imaging application.
ISSN:0256-7679
1439-6203
DOI:10.1007/s10118-014-1537-3