THE USE OF CITRIC ACID DIALYSATE IN OUR DIALYSIS CENTER: PRELIMINARY EXPERIENCE

Background: Citric acid dialysate (CD) is a dialysis acid concentrate for bicarbonate-based dialysis containing citrate instead of acetate as the primary acidifying agent. The aim of our study was to compare the impact of citrate- and acetate-based dialysates on acid-base status, rate of inflammatio...

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Bibliographic Details
Published in:International journal of artificial organs 2014-01, Vol.37 (8), p.617-617
Main Authors: Romozi, K, Ponikvar, R, Gubensek, J, Knap, B, Marn, A, Kveder, M, Lesevic, N, Skofic, N, Zupunski, A, Benedik, M, Buturovic, J
Format: Article
Language:English
Subjects:
Acetates
Bicarbonates
Calcium
Citrates
Citric acid
Dialysis
Patients
Switching
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Summary:Background: Citric acid dialysate (CD) is a dialysis acid concentrate for bicarbonate-based dialysis containing citrate instead of acetate as the primary acidifying agent. The aim of our study was to compare the impact of citrate- and acetate-based dialysates on acid-base status, rate of inflammation, calcium balance and dialysis efficiency. Methods: We retrospectively evaluated 99 chronic hemodialysis patients treated during the months of Dec 2012 and Sept 2013. Before the switch to CD, all of the clinics used regular bicarbonate dialysate acidified with acetic acid. Regular pre-dialysis biochemical data were gathered a month before and after switching to CD. Results: Subjects were 63% male, mean age was 62 + or - 15 (range 26-92) years. After switching to CD, there was an increase in total CO sub(2) level from 22.9 + or - 3 to 24.8 + or - 3.7 mmol/l (p
ISSN:0391-3988
DOI:10.5301/ijao.5000347