Polyphenols in Health and Disease

Deadly diseases, such as cardiovascular diseases and cancer, remain the major health problems worldwide. Research in cardiovascular diseases and genome-wide association studies were successful in indentifying the gene loci associated with these threatening diseases. Yet, a substantial number of casu...

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Bibliographic Details
Published in:Cell biochemistry and biophysics 2015-12, Vol.73 (3), p.649-664
Main Author: Zhang, Pei-Ying
Format: Article
Language:English
Subjects:
Animals
Anti-Inflammatory Agents, Non-Steroidal - pharmacology
Anti-Inflammatory Agents, Non-Steroidal - therapeutic use
Antineoplastic Agents, Phytogenic - pharmacology
Antineoplastic Agents, Phytogenic - therapeutic use
Antioxidants - pharmacology
Antioxidants - therapeutic use
Biochemistry
Biological and Medical Physics
Biomedical and Life Sciences
Biophysics
Biotechnology
Cardiotonic Agents - pharmacology
Cardiotonic Agents - therapeutic use
Cardiovascular diseases
Cell Biology
Enzyme Inhibitors - pharmacology
Enzyme Inhibitors - therapeutic use
Health problems
Humans
Life Sciences
Molecular Targeted Therapy - methods
Original Paper
Pharmacology/Toxicology
Polyphenols - pharmacology
Polyphenols - therapeutic use
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Summary:Deadly diseases, such as cardiovascular diseases and cancer, remain the major health problems worldwide. Research in cardiovascular diseases and genome-wide association studies were successful in indentifying the gene loci associated with these threatening diseases. Yet, a substantial number of casual factors remain unexplained. Over the last decade, a better understanding of molecular and biochemical mechanisms of cardiac diseases led to developing a rationale for combining various protective agents, such as polyphenols, to target multiple signaling pathways. The present review article summarizes recent advances of the use of polyphenols against diseases, such as cardiac diseases.
ISSN:1085-9195
1559-0283
DOI:10.1007/s12013-015-0558-z