Diagnostic value of strain elastography for differentiation between renal cell carcinoma and transitional cell carcinoma of kidney

• Published in: Abdominal imaging 2016-06, Vol.41 (6), p.1152-1159
• Main Authors: Inci, Mehmet Fatih, Kalayci, Tugce Ozlem, Tan, Sinan, Karasu, Sebnem, Albayrak, Eda, Cakir, Volkan, Ocal, Irfan, Ozkan, Fuat
• Format: Article
• Language: English
• Subjects: Aged; Carcinoma, Renal Cell - diagnostic imaging; Carcinoma, Renal Cell - pathology; Carcinoma, Transitional Cell - diagnostic imaging; Carcinoma, Transitional Cell - pathology; Diagnosis, Differential; Elasticity Imaging Techniques; Female; Gastroenterology; Hepatology; Humans; Imaging; Kidney Neoplasms - diagnostic imaging; Kidney Neoplasms - pathology; Male; Medicine; Medicine & Public Health; Middle Aged; Prospective Studies; Radiology; Sensitivity and Specificity
• ISSN: 2366-004X; 2366-0058
• DOI: 10.1007/s00261-016-0658-2

Purpose The objective of our study was to prospectively evaluate the diagnostic performance of strain elastography for differentiation between renal cell carcinomas (RCCs) and transitional cell carcinomas (TCCs) of kidney. Methods A total of 99 consecutive patients who were referred to our hospital because of a newly diagnosed solid renal mass suspicious for malignancy on radiological screenings were evaluated with sonography, including strain elastography. Strain elastography was used to compare the stiffness of the renal masses and renal cortex. The ratio of strain in a renal mass and nearby renal cortex was defined as the strain index value. Mean strain index values for RCCs and TCCs were compared, and mean strain index values between histological subtypes of RCC were also compared. Results Although TCCs were smaller than RCCs ( p