Severe macrolide-resistant Mycoplasma pneumoniae pneumonia associated with macrolide failure

We investigated differences in outcomes between 68 children hospitalized with macrolide-sensitive Mycoplasma pneumoniae pneumonia (MSMP group) and 25 children hospitalized with macrolide-resistant M. pneumoniae pneumonia (MRMP group). In the MRMP group, 19 children received macrolides and clinical f...

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Bibliographic Details
Published in:Journal of microbiology, immunology and infection immunology and infection, 2016-02, Vol.49 (1), p.127-130
Main Authors: Cheong, Kai-Ning, Chiu, Susan S, Chan, Betsy Wai-Ka, To, Kelvin Kai-Wang, Chan, Eunice Lai-Yin, Ho, Pak-Leung
Format: Article
Language:English
Subjects:
Adolescent
Anti-Bacterial Agents - pharmacology
Anti-Bacterial Agents - therapeutic use
atypical pneumonia
Child
Child, Preschool
Drug Resistance, Bacterial
empyema
Female
Humans
Infant
Infectious Disease
macrolides
Macrolides - pharmacology
Macrolides - therapeutic use
Male
Medical Education
Mycoplasma pneumoniae
Mycoplasma pneumoniae - drug effects
Mycoplasma pneumoniae - isolation & purification
Pneumonia, Mycoplasma - diagnosis
Pneumonia, Mycoplasma - drug therapy
Pneumonia, Mycoplasma - microbiology
Treatment Failure
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Summary:We investigated differences in outcomes between 68 children hospitalized with macrolide-sensitive Mycoplasma pneumoniae pneumonia (MSMP group) and 25 children hospitalized with macrolide-resistant M. pneumoniae pneumonia (MRMP group). In the MRMP group, 19 children received macrolides and clinical failure occurred in six of which five had pneumonia progression during therapy.
ISSN:1684-1182
1995-9133
DOI:10.1016/j.jmii.2014.11.003