The Natural History of Thoracic Aortic Disease: So Much Left to Learn

[...]experts postulated that BAV-associated aneurysms were likely virulent and akin to the aortic root aneurysms seen in Marfan syndrome (MFS), which prompted the authors of the 2010 American College of Cardiology/American Heart Association (ACC/AHA) Guidelines for the Diagnosis and Management of Pa...

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Bibliographic Details
Published in:Journal of the American College of Cardiology 2016-06, Vol.67 (23), p.2755-2757
Main Author: Isselbacher, Eric M.
Format: Article
Language:English
Subjects:
Aneurysm, Dissecting
Aneurysms
Aorta
Aortic Aneurysm
Aortic Aneurysm, Thoracic
aortic dissection
Aortic Valve
bicuspid aortic valve
Cardiology
Coronary vessels
Humans
Marfan Syndrome
Medical imaging
Patients
Studies
thoracic aortic aneurysm
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Summary:[...]experts postulated that BAV-associated aneurysms were likely virulent and akin to the aortic root aneurysms seen in Marfan syndrome (MFS), which prompted the authors of the 2010 American College of Cardiology/American Heart Association (ACC/AHA) Guidelines for the Diagnosis and Management of Patients With Thoracic Aortic Disease to lower the threshold for aortic repair in those with a BAV to 5.0 cm (down from the traditional 5.5 cm), with consideration of surgery even at diameters as low as 4.0 cm in certain clinical settings (1). In the current study, 15 of 22 type B AoD occurred in patients with MFS and none in those with BAV. Because it has been well established that patients with MFS and aortic root aneurysms are at high risk for AoD at young ages, the primary therapeutic strategy has been the timely repair of aneurysms of >=5.0 cm.
ISSN:0735-1097
1558-3597
DOI:10.1016/j.jacc.2016.04.007