A stroke of insight from genetics

For a disorder such as schizophrenia, a sample size of about 3000 people led to the discovery of a single locus in 2009,3 but only 5 years later, a huge international collaborative effort combined data for 35 000 people and identified 108 loci.4 Therefore, in human genetics studies on complex traits...

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Bibliographic Details
Published in:Lancet neurology 2016-06, Vol.15 (7), p.653-654
Main Authors: Visscher, Peter M, Veldink, Jan H
Format: Article
Language:English
Subjects:
Disease
Gene loci
Genetics
Genomes
Neurology
Researchers
Schizophrenia
Stroke
Studies
Citations: Items that this one cites
Online Access:Get full text
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Summary:For a disorder such as schizophrenia, a sample size of about 3000 people led to the discovery of a single locus in 2009,3 but only 5 years later, a huge international collaborative effort combined data for 35 000 people and identified 108 loci.4 Therefore, in human genetics studies on complex traits, researchers aim to obtain ever growing sample sizes that allow genetic evidence to grow as well.
ISSN:1474-4422
1474-4465
DOI:10.1016/S1474-4422(16)30028-X