Loading…

Broad-Spectrum Liquid- and Gas-Phase Decontamination of Chemical Warfare Agents by One-Dimensional Heteropolyniobates

A wide range of chemical warfare agents and their simulants are catalytically decontaminated by a new one‐dimensional polymeric polyniobate (P‐PONb), K12[Ti2O2][GeNb12O40]⋅19 H2O (KGeNb) under mild conditions and in the dark. Uniquely, KGeNb facilitates hydrolysis of nerve agents Sarin (GB) and Soma...

Full description

Saved in:
Bibliographic Details
Published in:Angewandte Chemie International Edition 2016-06, Vol.55 (26), p.7403-7407
Main Authors: Guo, Weiwei, Lv, Hongjin, Sullivan, Kevin P., Gordon, Wesley O., Balboa, Alex, Wagner, George W., Musaev, Djamaladdin G., Bacsa, John, Hill, Craig L.
Format: Article
Language:English
Subjects:
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c5460-957b1c130e9b516aff8f515ed3717cb5d990fda4c7edc1e37a4f3a9745cd73e63
cites cdi_FETCH-LOGICAL-c5460-957b1c130e9b516aff8f515ed3717cb5d990fda4c7edc1e37a4f3a9745cd73e63
container_end_page 7407
container_issue 26
container_start_page 7403
container_title Angewandte Chemie International Edition
container_volume 55
creator Guo, Weiwei
Lv, Hongjin
Sullivan, Kevin P.
Gordon, Wesley O.
Balboa, Alex
Wagner, George W.
Musaev, Djamaladdin G.
Bacsa, John
Hill, Craig L.
description A wide range of chemical warfare agents and their simulants are catalytically decontaminated by a new one‐dimensional polymeric polyniobate (P‐PONb), K12[Ti2O2][GeNb12O40]⋅19 H2O (KGeNb) under mild conditions and in the dark. Uniquely, KGeNb facilitates hydrolysis of nerve agents Sarin (GB) and Soman (GD) (and their less reactive simulants, dimethyl methylphosphonate (DMMP)) as well as mustard (HD) in both liquid and gas phases at ambient temperature and in the absence of neutralizing bases or illumination. Three lines of evidence establish that KGeNb removes DMMP, and thus likely GB/GD, by general base catalysis: a) the k(H2O)/k(D2O) solvent isotope effect is 1.4; b) the rate law (hydrolysis at the same pH depends on the amount of P‐PONb present); and c) hydroxide is far less active against the above simulants at the same pH than the P‐PONbs themselves, a critical control experiment. POM against CWAs: A new one‐dimensional polymeric polyniobate, K12[Ti2O2][GeNb12O40], removes a wide range of chemical warfare agents (CWAs) and their simulants. The transformations are catalytic and proceed effectively under very mild conditions and in the dark.
doi_str_mv 10.1002/anie.201601620
format article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1797866532</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>4089397831</sourcerecordid><originalsourceid>FETCH-LOGICAL-c5460-957b1c130e9b516aff8f515ed3717cb5d990fda4c7edc1e37a4f3a9745cd73e63</originalsourceid><addsrcrecordid>eNqF0cFv0zAUBvAIgdgYXDkiS1y4uNhx7Rcfu250k6ptoqAdLcd5YR5J3NmJoP89njoqxAEkS_bh9z5Z7yuKt5zNOGPlRzt4nJWMq3xK9qw45rLkVACI5_k9F4JCJflR8Sql--yriqmXxVEJTHGtxHExncZgG7rZohvj1JO1f5h8Q4kdGrKyid7c2YTkDF0YRtv7wY4-DCS0ZHmHvXe2I7c2tjYiWXzDYUyk3pHrAemZ73FI2WZxgSPGsA3dbvChtiOm18WL1nYJ3zzdJ8XXT-dflhd0fb26XC7W1Mm5YlRLqLnjgqGuJVe2batWcomNAA6ulo3WrG3s3AE2jqMAO2-F1TCXrgGBSpwUH_a52xgeJkyj6X1y2HV2wDAlw0FDpZQUZabv_6L3YYr5-1lpVpUgQfN_KtAK8t65yGq2Vy6GlCK2Zht9b-POcGYeazOPtZlDbXng3VPsVPfYHPjvnjLQe_DDd7j7T5xZXF2e_xlO97M-jfjzMGvjd6NAgDS3VyuzWZ9-voGNMlL8AgPessE</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1796777313</pqid></control><display><type>article</type><title>Broad-Spectrum Liquid- and Gas-Phase Decontamination of Chemical Warfare Agents by One-Dimensional Heteropolyniobates</title><source>Wiley</source><creator>Guo, Weiwei ; Lv, Hongjin ; Sullivan, Kevin P. ; Gordon, Wesley O. ; Balboa, Alex ; Wagner, George W. ; Musaev, Djamaladdin G. ; Bacsa, John ; Hill, Craig L.</creator><creatorcontrib>Guo, Weiwei ; Lv, Hongjin ; Sullivan, Kevin P. ; Gordon, Wesley O. ; Balboa, Alex ; Wagner, George W. ; Musaev, Djamaladdin G. ; Bacsa, John ; Hill, Craig L.</creatorcontrib><description>A wide range of chemical warfare agents and their simulants are catalytically decontaminated by a new one‐dimensional polymeric polyniobate (P‐PONb), K12[Ti2O2][GeNb12O40]⋅19 H2O (KGeNb) under mild conditions and in the dark. Uniquely, KGeNb facilitates hydrolysis of nerve agents Sarin (GB) and Soman (GD) (and their less reactive simulants, dimethyl methylphosphonate (DMMP)) as well as mustard (HD) in both liquid and gas phases at ambient temperature and in the absence of neutralizing bases or illumination. Three lines of evidence establish that KGeNb removes DMMP, and thus likely GB/GD, by general base catalysis: a) the k(H2O)/k(D2O) solvent isotope effect is 1.4; b) the rate law (hydrolysis at the same pH depends on the amount of P‐PONb present); and c) hydroxide is far less active against the above simulants at the same pH than the P‐PONbs themselves, a critical control experiment. POM against CWAs: A new one‐dimensional polymeric polyniobate, K12[Ti2O2][GeNb12O40], removes a wide range of chemical warfare agents (CWAs) and their simulants. The transformations are catalytic and proceed effectively under very mild conditions and in the dark.</description><edition>International ed. in English</edition><identifier>ISSN: 1433-7851</identifier><identifier>EISSN: 1521-3773</identifier><identifier>DOI: 10.1002/anie.201601620</identifier><identifier>PMID: 27061963</identifier><identifier>CODEN: ACIEAY</identifier><language>eng</language><publisher>Germany: Blackwell Publishing Ltd</publisher><subject>Ambient temperature ; Biological &amp; chemical weapons ; Catalysis ; Chemical warfare ; Chemical warfare agents ; Decontamination ; heteropolyniobates ; Hydrolysis ; Illumination ; Isotope effect ; Mustard ; Nerve agents ; Neutralizing ; Sarin ; Soman ; Temperature effects ; Vapor phases</subject><ispartof>Angewandte Chemie International Edition, 2016-06, Vol.55 (26), p.7403-7407</ispartof><rights>2016 WILEY‐VCH Verlag GmbH &amp; Co. KGaA, Weinheim</rights><rights>2016 WILEY-VCH Verlag GmbH &amp; Co. KGaA, Weinheim.</rights><rights>2016 WILEY-VCH Verlag GmbH &amp; Co. KGaA, Weinheim</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5460-957b1c130e9b516aff8f515ed3717cb5d990fda4c7edc1e37a4f3a9745cd73e63</citedby><cites>FETCH-LOGICAL-c5460-957b1c130e9b516aff8f515ed3717cb5d990fda4c7edc1e37a4f3a9745cd73e63</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27061963$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Guo, Weiwei</creatorcontrib><creatorcontrib>Lv, Hongjin</creatorcontrib><creatorcontrib>Sullivan, Kevin P.</creatorcontrib><creatorcontrib>Gordon, Wesley O.</creatorcontrib><creatorcontrib>Balboa, Alex</creatorcontrib><creatorcontrib>Wagner, George W.</creatorcontrib><creatorcontrib>Musaev, Djamaladdin G.</creatorcontrib><creatorcontrib>Bacsa, John</creatorcontrib><creatorcontrib>Hill, Craig L.</creatorcontrib><title>Broad-Spectrum Liquid- and Gas-Phase Decontamination of Chemical Warfare Agents by One-Dimensional Heteropolyniobates</title><title>Angewandte Chemie International Edition</title><addtitle>Angew. Chem. Int. Ed</addtitle><description>A wide range of chemical warfare agents and their simulants are catalytically decontaminated by a new one‐dimensional polymeric polyniobate (P‐PONb), K12[Ti2O2][GeNb12O40]⋅19 H2O (KGeNb) under mild conditions and in the dark. Uniquely, KGeNb facilitates hydrolysis of nerve agents Sarin (GB) and Soman (GD) (and their less reactive simulants, dimethyl methylphosphonate (DMMP)) as well as mustard (HD) in both liquid and gas phases at ambient temperature and in the absence of neutralizing bases or illumination. Three lines of evidence establish that KGeNb removes DMMP, and thus likely GB/GD, by general base catalysis: a) the k(H2O)/k(D2O) solvent isotope effect is 1.4; b) the rate law (hydrolysis at the same pH depends on the amount of P‐PONb present); and c) hydroxide is far less active against the above simulants at the same pH than the P‐PONbs themselves, a critical control experiment. POM against CWAs: A new one‐dimensional polymeric polyniobate, K12[Ti2O2][GeNb12O40], removes a wide range of chemical warfare agents (CWAs) and their simulants. The transformations are catalytic and proceed effectively under very mild conditions and in the dark.</description><subject>Ambient temperature</subject><subject>Biological &amp; chemical weapons</subject><subject>Catalysis</subject><subject>Chemical warfare</subject><subject>Chemical warfare agents</subject><subject>Decontamination</subject><subject>heteropolyniobates</subject><subject>Hydrolysis</subject><subject>Illumination</subject><subject>Isotope effect</subject><subject>Mustard</subject><subject>Nerve agents</subject><subject>Neutralizing</subject><subject>Sarin</subject><subject>Soman</subject><subject>Temperature effects</subject><subject>Vapor phases</subject><issn>1433-7851</issn><issn>1521-3773</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><recordid>eNqF0cFv0zAUBvAIgdgYXDkiS1y4uNhx7Rcfu250k6ptoqAdLcd5YR5J3NmJoP89njoqxAEkS_bh9z5Z7yuKt5zNOGPlRzt4nJWMq3xK9qw45rLkVACI5_k9F4JCJflR8Sql--yriqmXxVEJTHGtxHExncZgG7rZohvj1JO1f5h8Q4kdGrKyid7c2YTkDF0YRtv7wY4-DCS0ZHmHvXe2I7c2tjYiWXzDYUyk3pHrAemZ73FI2WZxgSPGsA3dbvChtiOm18WL1nYJ3zzdJ8XXT-dflhd0fb26XC7W1Mm5YlRLqLnjgqGuJVe2batWcomNAA6ulo3WrG3s3AE2jqMAO2-F1TCXrgGBSpwUH_a52xgeJkyj6X1y2HV2wDAlw0FDpZQUZabv_6L3YYr5-1lpVpUgQfN_KtAK8t65yGq2Vy6GlCK2Zht9b-POcGYeazOPtZlDbXng3VPsVPfYHPjvnjLQe_DDd7j7T5xZXF2e_xlO97M-jfjzMGvjd6NAgDS3VyuzWZ9-voGNMlL8AgPessE</recordid><startdate>20160620</startdate><enddate>20160620</enddate><creator>Guo, Weiwei</creator><creator>Lv, Hongjin</creator><creator>Sullivan, Kevin P.</creator><creator>Gordon, Wesley O.</creator><creator>Balboa, Alex</creator><creator>Wagner, George W.</creator><creator>Musaev, Djamaladdin G.</creator><creator>Bacsa, John</creator><creator>Hill, Craig L.</creator><general>Blackwell Publishing Ltd</general><general>Wiley Subscription Services, Inc</general><scope>BSCLL</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TM</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>20160620</creationdate><title>Broad-Spectrum Liquid- and Gas-Phase Decontamination of Chemical Warfare Agents by One-Dimensional Heteropolyniobates</title><author>Guo, Weiwei ; Lv, Hongjin ; Sullivan, Kevin P. ; Gordon, Wesley O. ; Balboa, Alex ; Wagner, George W. ; Musaev, Djamaladdin G. ; Bacsa, John ; Hill, Craig L.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5460-957b1c130e9b516aff8f515ed3717cb5d990fda4c7edc1e37a4f3a9745cd73e63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Ambient temperature</topic><topic>Biological &amp; chemical weapons</topic><topic>Catalysis</topic><topic>Chemical warfare</topic><topic>Chemical warfare agents</topic><topic>Decontamination</topic><topic>heteropolyniobates</topic><topic>Hydrolysis</topic><topic>Illumination</topic><topic>Isotope effect</topic><topic>Mustard</topic><topic>Nerve agents</topic><topic>Neutralizing</topic><topic>Sarin</topic><topic>Soman</topic><topic>Temperature effects</topic><topic>Vapor phases</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Guo, Weiwei</creatorcontrib><creatorcontrib>Lv, Hongjin</creatorcontrib><creatorcontrib>Sullivan, Kevin P.</creatorcontrib><creatorcontrib>Gordon, Wesley O.</creatorcontrib><creatorcontrib>Balboa, Alex</creatorcontrib><creatorcontrib>Wagner, George W.</creatorcontrib><creatorcontrib>Musaev, Djamaladdin G.</creatorcontrib><creatorcontrib>Bacsa, John</creatorcontrib><creatorcontrib>Hill, Craig L.</creatorcontrib><collection>Istex</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Nucleic Acids Abstracts</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Angewandte Chemie International Edition</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Guo, Weiwei</au><au>Lv, Hongjin</au><au>Sullivan, Kevin P.</au><au>Gordon, Wesley O.</au><au>Balboa, Alex</au><au>Wagner, George W.</au><au>Musaev, Djamaladdin G.</au><au>Bacsa, John</au><au>Hill, Craig L.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Broad-Spectrum Liquid- and Gas-Phase Decontamination of Chemical Warfare Agents by One-Dimensional Heteropolyniobates</atitle><jtitle>Angewandte Chemie International Edition</jtitle><addtitle>Angew. Chem. Int. Ed</addtitle><date>2016-06-20</date><risdate>2016</risdate><volume>55</volume><issue>26</issue><spage>7403</spage><epage>7407</epage><pages>7403-7407</pages><issn>1433-7851</issn><eissn>1521-3773</eissn><coden>ACIEAY</coden><abstract>A wide range of chemical warfare agents and their simulants are catalytically decontaminated by a new one‐dimensional polymeric polyniobate (P‐PONb), K12[Ti2O2][GeNb12O40]⋅19 H2O (KGeNb) under mild conditions and in the dark. Uniquely, KGeNb facilitates hydrolysis of nerve agents Sarin (GB) and Soman (GD) (and their less reactive simulants, dimethyl methylphosphonate (DMMP)) as well as mustard (HD) in both liquid and gas phases at ambient temperature and in the absence of neutralizing bases or illumination. Three lines of evidence establish that KGeNb removes DMMP, and thus likely GB/GD, by general base catalysis: a) the k(H2O)/k(D2O) solvent isotope effect is 1.4; b) the rate law (hydrolysis at the same pH depends on the amount of P‐PONb present); and c) hydroxide is far less active against the above simulants at the same pH than the P‐PONbs themselves, a critical control experiment. POM against CWAs: A new one‐dimensional polymeric polyniobate, K12[Ti2O2][GeNb12O40], removes a wide range of chemical warfare agents (CWAs) and their simulants. The transformations are catalytic and proceed effectively under very mild conditions and in the dark.</abstract><cop>Germany</cop><pub>Blackwell Publishing Ltd</pub><pmid>27061963</pmid><doi>10.1002/anie.201601620</doi><tpages>5</tpages><edition>International ed. in English</edition></addata></record>
fulltext fulltext
identifier ISSN: 1433-7851
ispartof Angewandte Chemie International Edition, 2016-06, Vol.55 (26), p.7403-7407
issn 1433-7851
1521-3773
language eng
recordid cdi_proquest_miscellaneous_1797866532
source Wiley
subjects Ambient temperature
Biological & chemical weapons
Catalysis
Chemical warfare
Chemical warfare agents
Decontamination
heteropolyniobates
Hydrolysis
Illumination
Isotope effect
Mustard
Nerve agents
Neutralizing
Sarin
Soman
Temperature effects
Vapor phases
title Broad-Spectrum Liquid- and Gas-Phase Decontamination of Chemical Warfare Agents by One-Dimensional Heteropolyniobates
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-31T04%3A45%3A33IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Broad-Spectrum%20Liquid-%20and%20Gas-Phase%20Decontamination%20of%20Chemical%20Warfare%20Agents%20by%20One-Dimensional%20Heteropolyniobates&rft.jtitle=Angewandte%20Chemie%20International%20Edition&rft.au=Guo,%20Weiwei&rft.date=2016-06-20&rft.volume=55&rft.issue=26&rft.spage=7403&rft.epage=7407&rft.pages=7403-7407&rft.issn=1433-7851&rft.eissn=1521-3773&rft.coden=ACIEAY&rft_id=info:doi/10.1002/anie.201601620&rft_dat=%3Cproquest_cross%3E4089397831%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c5460-957b1c130e9b516aff8f515ed3717cb5d990fda4c7edc1e37a4f3a9745cd73e63%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1796777313&rft_id=info:pmid/27061963&rfr_iscdi=true