Cystic Fibrosis-Related Diabetes with strict glycaemic control is not associated with frequent intravenous antibiotics use for pulmonary infections

Highlights • Long observation period of six years in 138 CF patients. • A CFRD population with strict glycaemic control (81% below target HbA1c). • IV antibiotics frequency is related to P. aeruginosa and impaired lung function. • No independent relation between well-controlled CFRD and IV antibioti...

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Bibliographic Details
Published in:Diabetes research and clinical practice 2016-06, Vol.116, p.230-236
Main Authors: Belle-van Meerkerk, G, de Valk, H.W, Stam-Slob, M.C, Teding van Berkhout, F, Zanen, P, van de Graaf, E.A
Format: Article
Language:English
Subjects:
Administration, Intravenous
Adolescent
Adult
Analysis of Variance
Anti-Bacterial Agents - administration & dosage
Blood Glucose - analysis
Case-Control Studies
Chronic Disease
Cystic Fibrosis - complications
Cystic Fibrosis-Related Diabetes
Diabetes Complications - epidemiology
Diabetes Mellitus - metabolism
Endocrinology & Metabolism
Female
Glycaemic control
Glycated Hemoglobin A - analysis
Glycemic Index
Humans
Hyperglycemia - complications
Hyperglycemia - prevention & control
Intravenous antibiotics
Lung Diseases - drug therapy
Lung Diseases - epidemiology
Male
Pulmonary infections
Retrospective Studies
Risk Factors
Young Adult
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Summary:Highlights • Long observation period of six years in 138 CF patients. • A CFRD population with strict glycaemic control (81% below target HbA1c). • IV antibiotics frequency is related to P. aeruginosa and impaired lung function. • No independent relation between well-controlled CFRD and IV antibiotics frequency. • There is a potential role of glycaemic control on infection frequency in CF patients.
ISSN:0168-8227
1872-8227
DOI:10.1016/j.diabres.2016.04.014