Performance of the abbreviated Reid colposcopic index in prediction of high-grade lesions

Abstract Objective To assess the diagnostic performance of the Reid colposcopic index (RCI) and establish the optimal cutoff value to predict a histology of cervical intraepithelial neoplasia grade 2 or worse (CIN2 +). Methods A retrospective analysis was undertaken of the medical records of women w...

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Bibliographic Details
Published in:International journal of gynecology and obstetrics 2016-07, Vol.134 (1), p.41-44
Main Author: Boonlikit, Sathone
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Aged, 80 and over
Cervical intraepithelial neoplasia
Cervical Intraepithelial Neoplasia - diagnosis
Cervical Intraepithelial Neoplasia - pathology
Colposcopic grading system
Colposcopy
Colposcopy - methods
Cutoff
Female
Humans
Logistic Models
Middle Aged
Neoplasm Grading
Obstetrics and Gynecology
Predictive Value of Tests
Reid colposcopic index
Retrospective Studies
ROC Curve
Sensitivity and Specificity
Severity of Illness Index
Thailand
Uterine Cervical Neoplasms - diagnosis
Uterine Cervical Neoplasms - pathology
Young Adult
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Summary:Abstract Objective To assess the diagnostic performance of the Reid colposcopic index (RCI) and establish the optimal cutoff value to predict a histology of cervical intraepithelial neoplasia grade 2 or worse (CIN2 +). Methods A retrospective analysis was undertaken of the medical records of women who underwent colposcopy with RCI scoring at a center in Bangkok, Thailand, between 2003 and 2014. Only patients for whom histology reports were available were included. Cases had been scored according to three criteria: margin, color, and vascular pattern. The performance of this three-criterion score (abbreviated RCI) was assessed for sensitivity, specificity, and positive and negative predictive values at every cutoff level. Receiver operation characteristics (ROC) curve analysis was performed to determine the optimal cutoff value to distinguish between women with CIN2 + and others. Results Among 349 included patients, 158 (45.3%) had CIN2 +. The most appropriate cutoff score was 3, which had a sensitivity of 72.7%, a specificity of 86.9%, and positive and negative predictive values of 82.1% and 79.4%, respectively. The area under ROC curve was 0.857 (95% confidence interval 0.815–0.898). Conclusion The performance of the abbreviated RCI seems satisfactory. The optimal cutoff value was 3.
ISSN:0020-7292
1879-3479
DOI:10.1016/j.ijgo.2015.10.025