Analyzing biomechanical parameters of the cornea with glaucoma severity in open-angle glaucoma

Purpose The purpose was to investigate a possible association of corneal hysteresis (CH) and corneal resistance factor (CRF) with open-angle glaucoma and the severity of disease. Methods In this prospective cross-sectional study we recruited 86 open-angle glaucoma patients, 16 patients with ocular h...

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Bibliographic Details
Published in:Graefe's archive for clinical and experimental ophthalmology 2016-07, Vol.254 (7), p.1345-1351
Main Authors: Pillunat, Karin R., Hermann, Cosima, Spoerl, Eberhard, Pillunat, Lutz E.
Format: Article
Language:English
Subjects:
Aged
Biomechanical Phenomena
Cornea - physiopathology
Cross-Sectional Studies
Female
Follow-Up Studies
Glaucoma
Glaucoma, Open-Angle - diagnosis
Glaucoma, Open-Angle - physiopathology
Humans
Intraocular Pressure - physiology
Male
Medicine
Medicine & Public Health
Middle Aged
Ophthalmology
Prospective Studies
Severity of Illness Index
Tonometry, Ocular
Visual Fields
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Summary:Purpose The purpose was to investigate a possible association of corneal hysteresis (CH) and corneal resistance factor (CRF) with open-angle glaucoma and the severity of disease. Methods In this prospective cross-sectional study we recruited 86 open-angle glaucoma patients, 16 patients with ocular hypertension (OHT,) and 44 age-matched controls. Each participant had a complete glaucoma workup including measurements with the Ocular Response Analyzer and computerized perimetry with the Humphrey 30–2 SITA Standard program. Visual field damage was based on mean deviation (MD) and considered as early glaucomatous with a MD > − 6 dB, moderate glaucomatous between −6 and −12 dB and advanced glaucomatous 
ISSN:0721-832X
1435-702X
DOI:10.1007/s00417-016-3365-3