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Azeotropic drying free [(18)F]FDG synthesis and its application to a lab-on-chip platform

A very simple and time-saving cartridge-based drying technique for [(18)F]fluoride allows for an efficient [(18)F]FDG synthesis using protic solvents and high water content. This novel method has been adapted to a lab-on-chip synthesis platform mitigating the standard azeotropic drying process and d...

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2016-01, Vol.52 (4), p.729-732
Main Authors: Lindner, S, Rensch, C, Neubaur, S, Neumeier, M, Salvamoser, R, Samper, V, Bartenstein, P
Format: Article
Language:English
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Summary:A very simple and time-saving cartridge-based drying technique for [(18)F]fluoride allows for an efficient [(18)F]FDG synthesis using protic solvents and high water content. This novel method has been adapted to a lab-on-chip synthesis platform mitigating the standard azeotropic drying process and demonstrating a proof of concept towards reduced hardware complexity for such systems.
ISSN:1359-7345
1364-548X
DOI:10.1039/c5cc07106b