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The evidence for low-dose CT screening of lung cancer

Abstract Lung cancer remains the leading cause of cancer-related death in the United States. An effective screening tool for early lung cancer detection has long been sought. Early chest radiograph and low-dose computed tomography (LDCT) screening trials were promising and demonstrated increased can...

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Published in:	Clinical imaging 2016-03, Vol.40 (2), p.288-295
Main Authors:	Ruchalski, Kathleen, Gutierrez, Antonio, Genshaft, Scott, Abtin, Fereidoun, Suh, Robert
Format:	Article
Language:	English
Subjects:	Cancer Cancer therapies Cellular biology Computation Early Detection of Cancer - methods Humans Imaging Lung cancer Lung cancer screening Lung Neoplasms - diagnostic imaging Lung-RADS Lungs Medical imaging Medical screening Morality Mortality Nelson NLST Ostomy Patients Radiation Dosage Radiographs Radiography Radiology Screening Smoking Studies Thoracic surgery Tomography Tomography, X-Ray Computed - methods Tumors
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container_title	Clinical imaging
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creator	Ruchalski, Kathleen Gutierrez, Antonio Genshaft, Scott Abtin, Fereidoun Suh, Robert
description	Abstract Lung cancer remains the leading cause of cancer-related death in the United States. An effective screening tool for early lung cancer detection has long been sought. Early chest radiograph and low-dose computed tomography (LDCT) screening trials were promising and demonstrated increased cancer detection. However, these studies were not able to improve lung cancer mortality. The National Lung Screening Trial resulted in decreased lung cancer mortality with LDCT screening in a high-risk population. Similar trials are currently underway in Europe. With LDCT now being widely implemented, it is paramount for radiologists to understand the evidence for lung cancer screening.
doi_str_mv	10.1016/j.clinimag.2015.07.001
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subjects	Cancer Cancer therapies Cellular biology Computation Early Detection of Cancer - methods Humans Imaging Lung cancer Lung cancer screening Lung Neoplasms - diagnostic imaging Lung-RADS Lungs Medical imaging Medical screening Morality Mortality Nelson NLST Ostomy Patients Radiation Dosage Radiographs Radiography Radiology Screening Smoking Studies Thoracic surgery Tomography Tomography, X-Ray Computed - methods Tumors
title	The evidence for low-dose CT screening of lung cancer
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