Evaluation of detoxification enzyme levels in Egyptian catfish, Clarias lazera, exposed to dimethoate

Egyptian catfish Clarias lazera were exposed to dimethoate, and detoxifying enzyme levels were measured. The fish were exposed to dimethoate at concentrations of .25 of, .5 of, and LC sub(50). Results showed that the reduced glutathione activity decreased in liver and kidney with increasing dimethoa...

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Bibliographic Details
Published in:Bulletin of environmental contamination and toxicology 1999-12, Vol.63 (6), p.789-796
Main Authors: Hamed, R.R, Elawa, S.E, Farid, N.M, Ataya, F.S
Format: Article
Language:English
Subjects:
Africa
Animals
Catfishes - metabolism
Clarias lazera
Detoxification
Dimethoate
Dimethoate - metabolism
Dimethoate - toxicity
Egypt
Egypt, Arab Rep
Egypt, Arab Rep., Nile R
Egypt, Nile R
Enzymes - metabolism
Freshwater
Gills - enzymology
Glutathione - metabolism
Glutathione Peroxidase - metabolism
Glutathione Reductase - metabolism
Glutathione Transferase - metabolism
Inactivation, Metabolic
Insecticides - metabolism
Insecticides - toxicity
Kidney - enzymology
Lethal Dose 50
Liver - enzymology
metabolic detoxification
Oxidation-Reduction
rivers
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Summary:Egyptian catfish Clarias lazera were exposed to dimethoate, and detoxifying enzyme levels were measured. The fish were exposed to dimethoate at concentrations of .25 of, .5 of, and LC sub(50). Results showed that the reduced glutathione activity decreased in liver and kidney with increasing dimethoate concentration. The levels of glutathione peroxidase and glutathione reductase in liver tissue were slightly affected by treatment. In kidney, the peroxidatic activity was reduced significantly in the presence of dimethoate.
ISSN:0007-4861
1432-0800
DOI:10.1007/s001289901048