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Spectral sensing for tissue diagnosis during lung biopsy procedures: the importance of an adequate internal reference and real-time feedback

Highlights • A method for biopsy guidance based on diffuse reflectance spectroscopy is presented. • The method relies on intrinsic optical contrast based on tissue composition. • Clinical feasibility was demonstrated during 23 routine lung biopsy procedures. • The integrated fiber-optic tool provide...

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Bibliographic Details
Published in:Lung cancer (Amsterdam, Netherlands) Netherlands), 2016-08, Vol.98, p.62-68
Main Authors: Spliethoff, Jarich W, Boer, Lisanne L.de, Meier, Mark A.J, Prevoo, Warner, Jong, Jeroen de, Bydlon, Torre M, Sterenborg, Henricus J.C.M, Burgers, Jacobus A, Hendriks, Benno H.W, Ruers, Theodoor J.M
Format: Article
Language:English
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Summary:Highlights • A method for biopsy guidance based on diffuse reflectance spectroscopy is presented. • The method relies on intrinsic optical contrast based on tissue composition. • Clinical feasibility was demonstrated during 23 routine lung biopsy procedures. • The integrated fiber-optic tool provided accurate real time tissue diagnosis.
ISSN:0169-5002
1872-8332
DOI:10.1016/j.lungcan.2016.05.019