Bilateral lower limb weakness in acute severe ulcerative colitis

An obese 49-year-old man with no medical history of note presented in August, 2014, with a 5-week history of bloody diarrhoea, anorexia, and unintentional weight loss. He reported passing 20 bloody stools per day, with nocturnal disturbance, and on admission had pyrexia, tachycardia, anaemia, and a...

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Bibliographic Details
Published in:The Lancet (British edition) 2016-07, Vol.388 (10039), p.101-102
Main Authors: Lynch, Ruairi W, MB, Soane, Timothy, PhD, Gibson, Rod, MB, Pal, Suvankar, MD, Lees, Charlie W, Dr
Format: Article
Language:English
Subjects:
Colitis, Ulcerative - complications
Colitis, Ulcerative - diagnosis
Colitis, Ulcerative - drug therapy
Cyclosporine - therapeutic use
Eating disorders
Epidural Space
Glucocorticoids - therapeutic use
Histopathology
Humans
Immunosuppressive Agents - therapeutic use
Inflammatory bowel disease
Internal Medicine
Legs
Lipomatosis - complications
Lipomatosis - diagnosis
Lower Extremity
Lumbar Vertebrae
Magnetic Resonance Imaging
Male
Medical diagnosis
Medical treatment
Middle Aged
Muscle Weakness - diagnosis
Muscle Weakness - etiology
Obesity - complications
Prednisolone - therapeutic use
Spinal Cord Compression - complications
Spinal Cord Compression - diagnosis
Thoracic Vertebrae
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Summary:An obese 49-year-old man with no medical history of note presented in August, 2014, with a 5-week history of bloody diarrhoea, anorexia, and unintentional weight loss. He reported passing 20 bloody stools per day, with nocturnal disturbance, and on admission had pyrexia, tachycardia, anaemia, and a robust inflammatory response. Flexible sigmoidoscopy showed severe confluent colitis, and histopathology confirmed a first presentation of active ulcerative colitis.
ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(16)30857-1