Meiosis: Cohesins Are Not Just for Sisters Any More

Multiple meiosis-specific cohesion proteins act to facilitate homolog segregation at the first meiotic division. A recent paper demonstrates that meiotic cohesins can be separated into two complexes, one that establishes and maintains intersister cohesion and one that promotes interhomolog adhesion...

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Bibliographic Details
Published in:Current biology 2016-07, Vol.26 (13), p.R523-R525
Main Authors: Cahoon, Cori K., Hawley, R. Scott
Format: Article
Language:English
Subjects:
Animals
Cell Cycle Proteins - metabolism
Chromosomal Proteins, Non-Histone - metabolism
Chromosome Pairing
Chromosome Segregation
Cohesins
Drosophila - cytology
Drosophila - metabolism
Meiosis
Sister Chromatid Exchange
Synaptonemal Complex
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Summary:Multiple meiosis-specific cohesion proteins act to facilitate homolog segregation at the first meiotic division. A recent paper demonstrates that meiotic cohesins can be separated into two complexes, one that establishes and maintains intersister cohesion and one that promotes interhomolog adhesion by regulating synaptonemal complex assembly. Multiple meiosis-specific cohesion proteins act to facilitate homolog segregation at the first meiotic division. A recent paper demonstrates that meiotic cohesins can be separated into two complexes, one that establishes and maintains intersister cohesion and one that promotes interhomolog adhesion by regulating synaptonemal complex assembly.
ISSN:0960-9822
1879-0445
DOI:10.1016/j.cub.2016.05.011