Effect of Cancer Symptoms and Fatigue on Chemotherapy-related Cognitive Impairment and Depression in People with Gastrointestinal Cancer

The purpose of this study was to test a hypothetical model of chemotherapy-related cognitive impairment (CRCI) and depression in people with gastrointestinal cancer. A purposive sample of 198 patients undergoing chemotherapy was recruited from November 2014 to July 2015. The instruments were Everyda...

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Bibliographic Details
Published in:Journal of Korean Academy of Nursing 2016-06, Vol.46 (3), p.420-430
Main Authors: Oh, Pok Ja, Lee, Jung Ran
Format: Article
Language:Korean
Subjects:
Adult
Aged
Anemia - etiology
Antineoplastic Agents - adverse effects
Antineoplastic Agents - therapeutic use
Anxiety
Camptothecin - adverse effects
Camptothecin - analogs & derivatives
Camptothecin - therapeutic use
Cognitive Dysfunction - etiology
Depression - etiology
Drug Therapy, Combination
Fatigue
Female
Fluorouracil - adverse effects
Fluorouracil - therapeutic use
Gastrointestinal Neoplasms - drug therapy
Gastrointestinal Neoplasms - pathology
Hemoglobins - metabolism
Humans
Male
Memory
Middle Aged
Nursing
Organoplatinum Compounds - adverse effects
Organoplatinum Compounds - therapeutic use
Paclitaxel - adverse effects
Paclitaxel - therapeutic use
Surveys and Questionnaires
Translating
Citations: Items that this one cites
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Summary:The purpose of this study was to test a hypothetical model of chemotherapy-related cognitive impairment (CRCI) and depression in people with gastrointestinal cancer. A purposive sample of 198 patients undergoing chemotherapy was recruited from November 2014 to July 2015. The instruments were Everyday Cognition (ECog), Hospital Anxiety Depression Scale (HADS), Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F), and M. D. Anderson Symptom Inventory-Gastrointestinal Cancer Module. Data were analyzed using descriptive statistics, correlation, and path analysis. CRCI was directly affected by cancer symptoms (β=.19, p=.004) and fatigue (β=.56, p
ISSN:2005-3673
2093-758X
DOI:10.4040/jkan.2016.46.3.420