Combined pulsed dye and CO2 lasers in the treatment of angiolymphoid hyperplasia with eosinophilia

• Published in: Lasers in medical science 2016-08, Vol.31 (6), p.1093-1096
• Main Authors: Sagi, Lior, Halachmi, Shlomit, Levi, Assi, Amitai, Dan Ben, Enk, Claes D., Lapidoth, Moshe
• Format: Article
• Language: English
• Subjects: Adult; Angiolymphoid Hyperplasia with Eosinophilia - pathology; Angiolymphoid Hyperplasia with Eosinophilia - rehabilitation; Carbon dioxide; Clinical outcomes; Combined Modality Therapy; Cryotherapy; Dentistry; Female; Humans; Lasers; Lasers, Dye - therapeutic use; Lasers, Gas - therapeutic use; Male; Medicine; Medicine & Public Health; Middle Aged; Neoplasm Recurrence, Local; Optical Devices; Optics; Original Article; Photonics; Quantum Optics; Skin diseases
• ISSN: 0268-8921; 1435-604X
• DOI: 10.1007/s10103-016-1954-3

Angiolymphoid hyperplasia with eosinophilia (ALHE) is an uncommon dermatosis of unknown etiology that manifests as characteristic red nodules and papules with a predilection for the scalp and periauricular region. Treatment is required for both esthetic and functional reasons, as lesions may ulcerate and bleed. Many treatment approaches have been reported, including excision, systemic medical approaches, topical or intralesional therapies, and non-invasive modalities including cryotherapy, electrosurgery, and laser. Treatments have exhibited variable efficacy, and the recurrence rate is 100 %. We report the combination of pulsed dye laser and CO 2 laser in the treatment of ALHE in 14 patients. All patients exhibited clinical response after a mean of 2.4 ± 0.4 treatment sessions. The clinical efficacy of the combined treatment, together with its well-tolerated nature, render the use of pulsed dye laser in combination with CO 2 laser, a viable treatment for debulking ALHE lesions. Ongoing maintenance treatments are needed to due to the high degree of relapse.