A comparison of endoscopy versus pathology sizing of colorectal adenomas and potential implications for surveillance colonoscopy

• Published in: Gastrointestinal endoscopy 2016-08, Vol.84 (2), p.341-351
• Main Authors: Taylor, Jennifer L, Coleman, Helen G, Gray, Ronan T, Kelly, Paul J, Cameron, R.I, O’Neill, Ciaran J, Shah, Rajeev M, Owen, Tracy A, Dickey, William, Loughrey, Maurice B
• Format: Article
• Language: English
• Subjects: Adenoma - pathology; Aged; Colonoscopy; Colorectal Neoplasms - pathology; Early Detection of Cancer; Female; Gastroenterology and Hepatology; Humans; Male; Middle Aged; Northern Ireland; Tumor Burden
• ISSN: 0016-5107; 1097-6779
• DOI: 10.1016/j.gie.2016.04.009

Abstract Background and Aims To compare endoscopy and pathology sizing in a large population-based series of colorectal adenomas and to evaluate the implications for patient stratification into surveillance colonoscopy. Methods Endoscopy and pathology sizes available from intact adenomas removed at colonoscopies performed as part of the Northern Ireland Bowel Cancer Screening Programme, from 2010 to 2015, were included in this study. Chi-squared tests were applied to compare size categories in relation to clinicopathological parameters and colonoscopy surveillance strata according to current American Gastroenterology Association and British Society of Gastroenterology guidelines. Results A total of 2521 adenomas from 1467 individuals were included. There was a trend toward larger endoscopy than pathology sizing in 4 of the 5 study centers, but overall sizing concordance was good. Significantly greater clustering with sizing to the nearest 5 mm was evident in endoscopy versus pathology sizing (30% vs 19%, p