In vitro ruminal fermentation of glycerol, propylene glycol and molasses combined with forages and their effect on glucose and insulin blood plasma concentrations after an oral drench in sheep

•The longer time to begin fermentation of glycerol allows for its absorption and its direct use for glucose production in the liver.•Propylene glycol and molasses increased proportion of propionate with the consequent reduction of the other volatile fatty acids.•Glycerol and propylene glycol increas...

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Published in:Animal feed science and technology 2016-03, Vol.213, p.74-80
Main Authors: Ferraro, S.M., Mendoza, G.D., Miranda, L.A., Gutiérrez, C.G.
Format: Article
Language:English
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Glucose
Glycerol
Insulin
Molasses
Propylene glycol
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cited_by cdi_FETCH-LOGICAL-c421t-475e5bc1524a98b2e64d63916bebce91ed2a8352684e88c2858360d536d3fa313
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creator Ferraro, S.M.
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description •The longer time to begin fermentation of glycerol allows for its absorption and its direct use for glucose production in the liver.•Propylene glycol and molasses increased proportion of propionate with the consequent reduction of the other volatile fatty acids.•Glycerol and propylene glycol increased glucose and insulin concentration in the plasma of sheep, whereas molasses did not. The in vitro gas production and the products of ruminal fermentation resulting from glycerol, propylene glycol and molasses energy additives combined with corn silage or alfalfa were evaluated. In addition, the effects of drenching with glycerol, propylene glycol and molasses on blood plasma concentrations of glucose and insulin in ewes were measured. Glycerol and propylene glycol showed a later onset of gas production than molasses (3.26h, 1.46h and 0.17h, respectively; P
doi_str_mv 10.1016/j.anifeedsci.2016.01.010
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The in vitro gas production and the products of ruminal fermentation resulting from glycerol, propylene glycol and molasses energy additives combined with corn silage or alfalfa were evaluated. In addition, the effects of drenching with glycerol, propylene glycol and molasses on blood plasma concentrations of glucose and insulin in ewes were measured. Glycerol and propylene glycol showed a later onset of gas production than molasses (3.26h, 1.46h and 0.17h, respectively; P<0.01). Regardless of the forage used, propylene glycol had the least volume of gas production (281mlg−1) compared to glycerol (397mlg−1) or molasses (402mlg−1; P<0.01). Fermentation with glycerol in vitro reduced the proportion of acetate and increased butyrate (P<0.01). Propylene glycol increased the proportion of propionate and reduced butyrate (P<0.01). 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The in vitro gas production and the products of ruminal fermentation resulting from glycerol, propylene glycol and molasses energy additives combined with corn silage or alfalfa were evaluated. In addition, the effects of drenching with glycerol, propylene glycol and molasses on blood plasma concentrations of glucose and insulin in ewes were measured. Glycerol and propylene glycol showed a later onset of gas production than molasses (3.26h, 1.46h and 0.17h, respectively; P<0.01). Regardless of the forage used, propylene glycol had the least volume of gas production (281mlg−1) compared to glycerol (397mlg−1) or molasses (402mlg−1; P<0.01). Fermentation with glycerol in vitro reduced the proportion of acetate and increased butyrate (P<0.01). Propylene glycol increased the proportion of propionate and reduced butyrate (P<0.01). Plasma glucose levels in vivo increased at 30 (P<0.01) and 60min (P<0.001), and remained elevated for 120 and 180min after of glycerol or propylene glycol oral administration. Similarly, insulin plasma concentrations increased significantly (P<0.05) at 30 and 90min, and remained elevated until 720min after glycerol and propylene glycol treatment (P<0.001). It was concluded that propylene glycol and glycerol have important glycogenic effects that may be facilitated by the long lag time that allows their absorption and direct conversion to glucose in the liver. Furthermore, the forage present during fermentation may influence the dynamics of such fermentation and suggests an association between forage and energy sources.]]></description><subject>Glucose</subject><subject>Glycerol</subject><subject>Insulin</subject><subject>Molasses</subject><subject>Propylene glycol</subject><issn>0377-8401</issn><issn>1873-2216</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><recordid>eNqFkcuu0zAQhiMEEuXAO8ySBSm-JKm7hCMuRzoSG1hbjj1uXTl2sJOD-nY8GtMWiSXySJb--efTXJoGONtyxof3p61JwSO6asNWkLJlnII9azZc7WQrBB-eNxsmd7tWdYy_bF7VemKMCyXFpvn9kOApLCVDWaeQTASPZcK0mCXkBNnDIZ4tlhzfwVzyfI6Y8KrlCCY5mHI0tWIFm6cxJHTwKyxH8LmYA6kXy3LEUAC9R7sAQQ9xtbniNRdSXWNIMMacHczEmgyhkqUWyrUHYvgFC7mBmBFcwWSPVAj1iDi_bl54Eyu--fvfNT8-f_p-_7V9_Pbl4f7DY2s7wZe22_XYj5b3ojN7NQocOjfIPR9GHC3uOTphlOzFoDpUygrVKzkw18vBSW8kl3fN2xuXtvBzxbroKVSLMZqEea2aK9b3jJ4iq7pZbcm1FvR6LmEy5aw505ej6ZP-dzR9OZpmnIJR6cdbKdIoTwGLJgfNiy4U2p52Ofwf8gfdA6oH</recordid><startdate>20160301</startdate><enddate>20160301</enddate><creator>Ferraro, S.M.</creator><creator>Mendoza, G.D.</creator><creator>Miranda, L.A.</creator><creator>Gutiérrez, C.G.</creator><general>Elsevier B.V</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>7T7</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>P64</scope></search><sort><creationdate>20160301</creationdate><title>In vitro ruminal fermentation of glycerol, propylene glycol and molasses combined with forages and their effect on glucose and insulin blood plasma concentrations after an oral drench in sheep</title><author>Ferraro, S.M. ; Mendoza, G.D. ; Miranda, L.A. ; Gutiérrez, C.G.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c421t-475e5bc1524a98b2e64d63916bebce91ed2a8352684e88c2858360d536d3fa313</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Glucose</topic><topic>Glycerol</topic><topic>Insulin</topic><topic>Molasses</topic><topic>Propylene glycol</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ferraro, S.M.</creatorcontrib><creatorcontrib>Mendoza, G.D.</creatorcontrib><creatorcontrib>Miranda, L.A.</creatorcontrib><creatorcontrib>Gutiérrez, C.G.</creatorcontrib><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><jtitle>Animal feed science and technology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ferraro, S.M.</au><au>Mendoza, G.D.</au><au>Miranda, L.A.</au><au>Gutiérrez, C.G.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>In vitro ruminal fermentation of glycerol, propylene glycol and molasses combined with forages and their effect on glucose and insulin blood plasma concentrations after an oral drench in sheep</atitle><jtitle>Animal feed science and technology</jtitle><date>2016-03-01</date><risdate>2016</risdate><volume>213</volume><spage>74</spage><epage>80</epage><pages>74-80</pages><issn>0377-8401</issn><eissn>1873-2216</eissn><abstract><![CDATA[•The longer time to begin fermentation of glycerol allows for its absorption and its direct use for glucose production in the liver.•Propylene glycol and molasses increased proportion of propionate with the consequent reduction of the other volatile fatty acids.•Glycerol and propylene glycol increased glucose and insulin concentration in the plasma of sheep, whereas molasses did not. The in vitro gas production and the products of ruminal fermentation resulting from glycerol, propylene glycol and molasses energy additives combined with corn silage or alfalfa were evaluated. In addition, the effects of drenching with glycerol, propylene glycol and molasses on blood plasma concentrations of glucose and insulin in ewes were measured. Glycerol and propylene glycol showed a later onset of gas production than molasses (3.26h, 1.46h and 0.17h, respectively; P<0.01). Regardless of the forage used, propylene glycol had the least volume of gas production (281mlg−1) compared to glycerol (397mlg−1) or molasses (402mlg−1; P<0.01). Fermentation with glycerol in vitro reduced the proportion of acetate and increased butyrate (P<0.01). Propylene glycol increased the proportion of propionate and reduced butyrate (P<0.01). 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source Elsevier:Jisc Collections:Elsevier Read and Publish Agreement 2022-2024:Freedom Collection (Reading list)
subjects Glucose
Glycerol
Insulin
Molasses
Propylene glycol
title In vitro ruminal fermentation of glycerol, propylene glycol and molasses combined with forages and their effect on glucose and insulin blood plasma concentrations after an oral drench in sheep
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