The profile of psychiatric symptoms exacerbated by methamphetamine use

Highlights • Methamphetamine use was associated with a dose-related exacerbation of positive psychotic, affective and psychomotor symptoms. • We found evidence of a latent symptom profile, comprised of positive psychotic and affective symptoms, that aligned with a diagnosis of substance-induced psyc...

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Bibliographic Details
Published in:Drug and alcohol dependence 2016-04, Vol.161, p.104-109
Main Authors: McKetin, Rebecca, Dawe, Sharon, Burns, Richard A, Hides, Leanne, Kavanagh, David J, Teesson, Maree, McD. Young, Ross, Voce, Alexandra, Saunders, John B
Format: Article
Language:English
Subjects:
Adult
Amphetamine
Amphetamine-Related Disorders - complications
Amphetamine-Related Disorders - diagnosis
Amphetamine-Related Disorders - psychology
Behavioral Symptoms - complications
Behavioral Symptoms - diagnosis
Behavioral Symptoms - psychology
Diagnostic and Statistical Manual of Mental Disorders
Female
Humans
Longitudinal Studies
Male
Mental Disorders - complications
Mental Disorders - diagnosis
Mental Disorders - psychology
Methamphetamine
Methamphetamine - adverse effects
Psychiatry
Psychoses, Substance-Induced - complications
Psychoses, Substance-Induced - diagnosis
Psychoses, Substance-Induced - psychology
Psychotic disorders
Schizophrenia
Substance-related disorders
Symptom Assessment
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Summary:Highlights • Methamphetamine use was associated with a dose-related exacerbation of positive psychotic, affective and psychomotor symptoms. • We found evidence of a latent symptom profile, comprised of positive psychotic and affective symptoms, that aligned with a diagnosis of substance-induced psychosis. • Methamphetamine use did not significantly increase the severity of negative symptoms of schizophrenia.
ISSN:0376-8716
1879-0046
DOI:10.1016/j.drugalcdep.2016.01.018