The Autoclaving of Autologous Bone is a Risk Factor for Surgical Site Infection after Cranioplasty

Highlights ● Cranioplasty with autoclaved autologous bone can cause surgical site infection rather than the prevention of infection. ● Autoclaving for autologous bone after long-term deep freezing can cause a loss of bone viability and may result in impaired immune reaction. ● The previous conflicti...

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Bibliographic Details
Published in:World neurosurgery 2016-07, Vol.91, p.43-49
Main Authors: Wui, Seong-Hyun, M.D, Kim, Kang Min, M.D, Ryu, Young-Joon, M.D, Kim, Inkyeong, M.D, Lee, Seung Jin, M.D, Kim, Jiha, M.D, Kim, Choonghyo, M.D, Park, Seoungwoo, M.D
Format: Article
Language:English
Subjects:
Adult
Aged
Autoclave
Bone Transplantation - adverse effects
Bone Transplantation - standards
Cranioplasty
Craniotomy - adverse effects
Craniotomy - standards
Female
Humans
Infection
Male
Middle Aged
Neurosurgery
Retrospective Studies
Surgical Flaps - adverse effects
Surgical Flaps - standards
Surgical Wound Infection - etiology
Surgical Wound Infection - prevention & control
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Summary:Highlights ● Cranioplasty with autoclaved autologous bone can cause surgical site infection rather than the prevention of infection. ● Autoclaving for autologous bone after long-term deep freezing can cause a loss of bone viability and may result in impaired immune reaction. ● The previous conflicting results with regard to the effectiveness of autoclaving may result from the difference of the bone preservation protocol.
ISSN:1878-8750
1878-8769
DOI:10.1016/j.wneu.2016.03.066