Prospective Comparison of Blood Culture Bottles and Conventional Swabs for Microbial Identification of Suspected Periprosthetic Joint Infection

Abstract Background Early, accurate detection of infection is vital to successful treatment of periprosthetic joint infection (PJI). Currently, no “gold standard” diagnostic testing exists. The goal of this prospective study was to compare the efficacy of a blood culture bottle system (BCBS) to comm...

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Bibliographic Details
Published in:The Journal of arthroplasty 2016-08, Vol.31 (8), p.1779-1783
Main Authors: Geller, Jeffrey A., MD, MacCallum, Katherine P., MD, Murtagh, Taylor S., BS, Patrick, David A., BS, Liabaud, Barthelemy, MD, Jonna, Venkata K., MD
Format: Article
Language:English
Subjects:
Adult
Aged
Arthritis, Infectious - diagnosis
Arthritis, Infectious - microbiology
Blood Culture - methods
blood culture bottles
Blood Sedimentation
C-Reactive Protein - analysis
conventional culture
diagnostic tool
Female
Humans
lower extremity arthroplasty
Male
Middle Aged
Orthopedics
periprosthetic joint infection
Prospective Studies
Prosthesis-Related Infections - diagnosis
Prosthesis-Related Infections - microbiology
Synovial Fluid - chemistry
Synovial Fluid - microbiology
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Summary:Abstract Background Early, accurate detection of infection is vital to successful treatment of periprosthetic joint infection (PJI). Currently, no “gold standard” diagnostic testing exists. The goal of this prospective study was to compare the efficacy of a blood culture bottle system (BCBS) to commonly used culture swabs in confirming PJI in patients with high clinical suspicion. Methods Patients were selected for enrollment based on Musculoskeletal Infection Society guidelines for PJI. ESR and CRP were obtained prior to aspiration. Aspirated fluid was divided between BCBS, swab, and synovial fluid analysis. Forty-nine samples were analyzed. Results BCBS yielded 41 positive cultures versus 19 with swab (p
ISSN:0883-5403
1532-8406
DOI:10.1016/j.arth.2016.02.014