Current Status and Future Prospects for Aptamer-Based Mycotoxin Detection

Aptamers are single-stranded oligonucleotides with the ability to bind tightly and selectively to a target analyte. High-affinity and specific aptamers for a variety of mycotoxins have been reported over the past decade. Increasingly, these molecular recognition elements are finding applications in...

Full description

Saved in:
Bibliographic Details
Published in:Journal of AOAC International 2016-07, Vol.99 (4), p.865-877
Main Authors: Ruscito, Annamaria, Smith, McKenzie, Goudreau, Daniel N, DeRosa, Maria C
Format: Article
Language:English
Subjects:
Aptamers, Nucleotide - chemistry
Biosensing Techniques - methods
Mycotoxins - analysis
SELEX Aptamer Technique - methods
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Aptamers are single-stranded oligonucleotides with the ability to bind tightly and selectively to a target analyte. High-affinity and specific aptamers for a variety of mycotoxins have been reported over the past decade. Increasingly, these molecular recognition elements are finding applications in biosensors and assays for the detection of mycotoxins in a variety of complex matrixes. This review article highlights the mycotoxin aptamers that are available for mycotoxin detection and the array of biosensing platforms into which they have been incorporated. Key advantages that aptamers have over analogous technology, and areas in which these advantages may be applied for the benefit of practical mycotoxin detection, are also discussed.
ISSN:1060-3271
1944-7922
DOI:10.5740/jaoacint.16-0114