Current Status and Future Prospects for Aptamer-Based Mycotoxin Detection

Aptamers are single-stranded oligonucleotides with the ability to bind tightly and selectively to a target analyte. High-affinity and specific aptamers for a variety of mycotoxins have been reported over the past decade. Increasingly, these molecular recognition elements are finding applications in...

Full description

Saved in:
Bibliographic Details
Published in:Journal of AOAC International 2016-07, Vol.99 (4), p.865-877
Main Authors: Ruscito, Annamaria, Smith, McKenzie, Goudreau, Daniel N, DeRosa, Maria C
Format: Article
Language:English
Subjects:
Aptamers, Nucleotide - chemistry
Biosensing Techniques - methods
Mycotoxins - analysis
SELEX Aptamer Technique - methods
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c299t-9b612b83bf33418cebb4c67248a9b46518e0d92602d14832b372c6008806d8da3
cites
container_end_page 877
container_issue 4
container_start_page 865
container_title Journal of AOAC International
container_volume 99
creator Ruscito, Annamaria
Smith, McKenzie
Goudreau, Daniel N
DeRosa, Maria C
description Aptamers are single-stranded oligonucleotides with the ability to bind tightly and selectively to a target analyte. High-affinity and specific aptamers for a variety of mycotoxins have been reported over the past decade. Increasingly, these molecular recognition elements are finding applications in biosensors and assays for the detection of mycotoxins in a variety of complex matrixes. This review article highlights the mycotoxin aptamers that are available for mycotoxin detection and the array of biosensing platforms into which they have been incorporated. Key advantages that aptamers have over analogous technology, and areas in which these advantages may be applied for the benefit of practical mycotoxin detection, are also discussed.
doi_str_mv 10.5740/jaoacint.16-0114
format article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1807274182</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1807274182</sourcerecordid><originalsourceid>FETCH-LOGICAL-c299t-9b612b83bf33418cebb4c67248a9b46518e0d92602d14832b372c6008806d8da3</originalsourceid><addsrcrecordid>eNo9kDtPwzAURi0EoqWwMyGPLCl-1XbGUihUKgIJmC3bcaRUTRz8kOi_J1VbpnuH83269wBwi9F0Jhh62GivbdOlKeYFwpidgTEuGStEScj5sCOOCkoEHoGrGDcIMcwRuQQjIiiWdMbHYLXIIbguwc-kU45QdxVc5pSDgx_Bx97ZFGHtA5z3SbcuFI86ugq-7axP_rfp4JNLA9P47hpc1Hob3c1xTsD38vlr8Vqs319Wi_m6sKQsU1EajomR1NSUMiytM4ZZLgiTujSMz7B0qCrJcGeFmaTEUEEsR0hKxCtZaToB94fePvif7GJSbROt225153yOCkskiBiqyYCiA2qHV2JwtepD0-qwUxipvUB1EqgwV3uBQ-Tu2J5N66r_wMkY_QOifGzm</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1807274182</pqid></control><display><type>article</type><title>Current Status and Future Prospects for Aptamer-Based Mycotoxin Detection</title><source>Oxford Journals Online</source><creator>Ruscito, Annamaria ; Smith, McKenzie ; Goudreau, Daniel N ; DeRosa, Maria C</creator><creatorcontrib>Ruscito, Annamaria ; Smith, McKenzie ; Goudreau, Daniel N ; DeRosa, Maria C</creatorcontrib><description>Aptamers are single-stranded oligonucleotides with the ability to bind tightly and selectively to a target analyte. High-affinity and specific aptamers for a variety of mycotoxins have been reported over the past decade. Increasingly, these molecular recognition elements are finding applications in biosensors and assays for the detection of mycotoxins in a variety of complex matrixes. This review article highlights the mycotoxin aptamers that are available for mycotoxin detection and the array of biosensing platforms into which they have been incorporated. Key advantages that aptamers have over analogous technology, and areas in which these advantages may be applied for the benefit of practical mycotoxin detection, are also discussed.</description><identifier>ISSN: 1060-3271</identifier><identifier>EISSN: 1944-7922</identifier><identifier>DOI: 10.5740/jaoacint.16-0114</identifier><identifier>PMID: 27318356</identifier><language>eng</language><publisher>England</publisher><subject>Aptamers, Nucleotide - chemistry ; Biosensing Techniques - methods ; Mycotoxins - analysis ; SELEX Aptamer Technique - methods</subject><ispartof>Journal of AOAC International, 2016-07, Vol.99 (4), p.865-877</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c299t-9b612b83bf33418cebb4c67248a9b46518e0d92602d14832b372c6008806d8da3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27318356$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ruscito, Annamaria</creatorcontrib><creatorcontrib>Smith, McKenzie</creatorcontrib><creatorcontrib>Goudreau, Daniel N</creatorcontrib><creatorcontrib>DeRosa, Maria C</creatorcontrib><title>Current Status and Future Prospects for Aptamer-Based Mycotoxin Detection</title><title>Journal of AOAC International</title><addtitle>J AOAC Int</addtitle><description>Aptamers are single-stranded oligonucleotides with the ability to bind tightly and selectively to a target analyte. High-affinity and specific aptamers for a variety of mycotoxins have been reported over the past decade. Increasingly, these molecular recognition elements are finding applications in biosensors and assays for the detection of mycotoxins in a variety of complex matrixes. This review article highlights the mycotoxin aptamers that are available for mycotoxin detection and the array of biosensing platforms into which they have been incorporated. Key advantages that aptamers have over analogous technology, and areas in which these advantages may be applied for the benefit of practical mycotoxin detection, are also discussed.</description><subject>Aptamers, Nucleotide - chemistry</subject><subject>Biosensing Techniques - methods</subject><subject>Mycotoxins - analysis</subject><subject>SELEX Aptamer Technique - methods</subject><issn>1060-3271</issn><issn>1944-7922</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><recordid>eNo9kDtPwzAURi0EoqWwMyGPLCl-1XbGUihUKgIJmC3bcaRUTRz8kOi_J1VbpnuH83269wBwi9F0Jhh62GivbdOlKeYFwpidgTEuGStEScj5sCOOCkoEHoGrGDcIMcwRuQQjIiiWdMbHYLXIIbguwc-kU45QdxVc5pSDgx_Bx97ZFGHtA5z3SbcuFI86ugq-7axP_rfp4JNLA9P47hpc1Hob3c1xTsD38vlr8Vqs319Wi_m6sKQsU1EajomR1NSUMiytM4ZZLgiTujSMz7B0qCrJcGeFmaTEUEEsR0hKxCtZaToB94fePvif7GJSbROt225153yOCkskiBiqyYCiA2qHV2JwtepD0-qwUxipvUB1EqgwV3uBQ-Tu2J5N66r_wMkY_QOifGzm</recordid><startdate>201607</startdate><enddate>201607</enddate><creator>Ruscito, Annamaria</creator><creator>Smith, McKenzie</creator><creator>Goudreau, Daniel N</creator><creator>DeRosa, Maria C</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201607</creationdate><title>Current Status and Future Prospects for Aptamer-Based Mycotoxin Detection</title><author>Ruscito, Annamaria ; Smith, McKenzie ; Goudreau, Daniel N ; DeRosa, Maria C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c299t-9b612b83bf33418cebb4c67248a9b46518e0d92602d14832b372c6008806d8da3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Aptamers, Nucleotide - chemistry</topic><topic>Biosensing Techniques - methods</topic><topic>Mycotoxins - analysis</topic><topic>SELEX Aptamer Technique - methods</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ruscito, Annamaria</creatorcontrib><creatorcontrib>Smith, McKenzie</creatorcontrib><creatorcontrib>Goudreau, Daniel N</creatorcontrib><creatorcontrib>DeRosa, Maria C</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of AOAC International</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ruscito, Annamaria</au><au>Smith, McKenzie</au><au>Goudreau, Daniel N</au><au>DeRosa, Maria C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Current Status and Future Prospects for Aptamer-Based Mycotoxin Detection</atitle><jtitle>Journal of AOAC International</jtitle><addtitle>J AOAC Int</addtitle><date>2016-07</date><risdate>2016</risdate><volume>99</volume><issue>4</issue><spage>865</spage><epage>877</epage><pages>865-877</pages><issn>1060-3271</issn><eissn>1944-7922</eissn><abstract>Aptamers are single-stranded oligonucleotides with the ability to bind tightly and selectively to a target analyte. High-affinity and specific aptamers for a variety of mycotoxins have been reported over the past decade. Increasingly, these molecular recognition elements are finding applications in biosensors and assays for the detection of mycotoxins in a variety of complex matrixes. This review article highlights the mycotoxin aptamers that are available for mycotoxin detection and the array of biosensing platforms into which they have been incorporated. Key advantages that aptamers have over analogous technology, and areas in which these advantages may be applied for the benefit of practical mycotoxin detection, are also discussed.</abstract><cop>England</cop><pmid>27318356</pmid><doi>10.5740/jaoacint.16-0114</doi><tpages>13</tpages></addata></record>
fulltext fulltext
identifier ISSN: 1060-3271
ispartof Journal of AOAC International, 2016-07, Vol.99 (4), p.865-877
issn 1060-3271
1944-7922
language eng
recordid cdi_proquest_miscellaneous_1807274182
source Oxford Journals Online
subjects Aptamers, Nucleotide - chemistry
Biosensing Techniques - methods
Mycotoxins - analysis
SELEX Aptamer Technique - methods
title Current Status and Future Prospects for Aptamer-Based Mycotoxin Detection
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-04T20%3A17%3A42IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Current%20Status%20and%20Future%20Prospects%20for%20Aptamer-Based%20Mycotoxin%20Detection&rft.jtitle=Journal%20of%20AOAC%20International&rft.au=Ruscito,%20Annamaria&rft.date=2016-07&rft.volume=99&rft.issue=4&rft.spage=865&rft.epage=877&rft.pages=865-877&rft.issn=1060-3271&rft.eissn=1944-7922&rft_id=info:doi/10.5740/jaoacint.16-0114&rft_dat=%3Cproquest_cross%3E1807274182%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c299t-9b612b83bf33418cebb4c67248a9b46518e0d92602d14832b372c6008806d8da3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1807274182&rft_id=info:pmid/27318356&rfr_iscdi=true