Pathogenicity and resistance islands of staphylococci

Variable genetic elements including plasmids, transposons and prophages are involved in pathogenesis and antibiotic resistance, and are an important component of the staphylococcal genome. This review covers a set of newly described variable chromosomal elements, pathogenicity and resistance islands...

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Bibliographic Details
Published in:Microbes and infection 2001-06, Vol.3 (7), p.585-594
Main Authors: Novick, Richard P., Schlievert, Patrick, Ruzin, Alexey
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents - pharmacology
Bacterial Toxins
Bacteriology
Base Sequence
Biological and medical sciences
Chromosomes, Bacterial - genetics
DNA, Bacterial - chemistry
Drug Resistance, Microbial - genetics
Enterotoxins - genetics
Enterotoxins - physiology
Evolution, Molecular
Fundamental and applied biological sciences. Psychology
Genetics
Genome, Bacterial
Humans
Methicillin Resistance - genetics
Microbial Sensitivity Tests
Microbiology
Molecular Sequence Data
MRSA
pathogenicity islands
resistance islands
Shock, Septic - microbiology
Staphylococcal Infections - drug therapy
Staphylococcal Infections - microbiology
Staphylococcus
Staphylococcus - drug effects
Staphylococcus - genetics
Staphylococcus - immunology
Staphylococcus - pathogenicity
Staphylococcus aureus
superantigens
Superantigens - genetics
Superantigens - physiology
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Summary:Variable genetic elements including plasmids, transposons and prophages are involved in pathogenesis and antibiotic resistance, and are an important component of the staphylococcal genome. This review covers a set of newly described variable chromosomal elements, pathogenicity and resistance islands, carrying superantigen and resistance genes, especially toxic shock and methicillin resistance, respectively.
ISSN:1286-4579
1769-714X
DOI:10.1016/S1286-4579(01)01414-9