Improved Efficacy by Addition of Protein-bound Polysaccharide K to Adjuvant Chemotherapy for Advanced Gastric Cancer

To evaluate the efficacy of protein-bound polysaccharide K (PSK) added to S-1 adjuvant chemotherapy for treatment of advanced gastric cancer. We retrospectively examined clinicopathological and recurrence-free survival (RFS) data for 136 patients with stage II or III advanced gastric cancer who unde...

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Bibliographic Details
Published in:Anticancer research 2016-08, Vol.36 (8), p.4237-4241
Main Authors: Fukuchi, Minoru, Mochiki, Erito, Ishiguro, Toru, Ogura, Toshiro, Sobajima, Jun, Kumagai, Youichi, Ishibashi, Keiichiro, Ishida, Hideyuki
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Antineoplastic Combined Chemotherapy Protocols - administration & dosage
Chemotherapy, Adjuvant
Disease-Free Survival
Drug Combinations
Female
Fungal Proteins - administration & dosage
Humans
Male
Middle Aged
Neoplasm Staging
Oxonic Acid - administration & dosage
Polysaccharides - administration & dosage
Postoperative Period
Stomach Neoplasms - drug therapy
Stomach Neoplasms - pathology
Stomach Neoplasms - surgery
Tegafur - administration & dosage
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Summary:To evaluate the efficacy of protein-bound polysaccharide K (PSK) added to S-1 adjuvant chemotherapy for treatment of advanced gastric cancer. We retrospectively examined clinicopathological and recurrence-free survival (RFS) data for 136 patients with stage II or III advanced gastric cancer who underwent S-1 adjuvant chemotherapy with or without PSK. Among 13 clinicopathological factors, non-T4 stage (odds ratio (OR)=0.61; 95% confidence interval (CI)=0.41-0.89; p
ISSN:1791-7530