From clinically relevant outcome measures to quality of life in epilepsy: a time trade-off study

Highlights • Development of population based utilities with the Time Trade Off method. • Clinically relevant epilepsy outcome measures are transformed into utility estimates. • Appropriate utility estimations for economic evaluations based on clinical outcomes. • Seizure severity is the most importa...

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Bibliographic Details
Published in:Epilepsy research 2016-09, Vol.125, p.24-31
Main Authors: de Kinderen, Reina J.A, Wijnen, Ben F.M, van Breukelen, Gerard, Postulart, Debby, Majoie, Marian H.J.M, Aldenkamp, Albert P, Evers, Silvia M.A.A
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Cohort Studies
Cost-Benefit Analysis
Cost-utility
Epilepsy
Epilepsy - complications
Epilepsy - diagnosis
Epilepsy - psychology
Epilepsy - therapy
Female
Humans
Male
Middle Aged
Netherlands
Neurology
Outcome Assessment (Health Care)
Preference-based
Quality of Life
Regression Analysis
Seizures - complications
Seizures - diagnosis
Seizures - psychology
Seizures - therapy
Severity of Illness Index
Time Factors
Time trade-off
Young Adult
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Summary:Highlights • Development of population based utilities with the Time Trade Off method. • Clinically relevant epilepsy outcome measures are transformed into utility estimates. • Appropriate utility estimations for economic evaluations based on clinical outcomes. • Seizure severity is the most important factor on utility.
ISSN:0920-1211
1872-6844
DOI:10.1016/j.eplepsyres.2016.05.005