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A luminescent europium(III)-platinum(II) heterometallic complex as a theranostic agent: a proof-of-concept study

A luminescent heterometallic multifunctional theranostic Eu-Pt2 complex [{cis-PtCl2(DMSO)}2Eu(L)(H2O)] has been synthesized, possessing two therapeutic Pt-centers as covalent DNA binders and one emissive Eu(3+)-center which is sensitized by platinum-based metal-to-ligand charge-transfer excited stat...

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Published in:Dalton transactions : an international journal of inorganic chemistry 2016-01, Vol.45 (2), p.494-497
Main Authors: Chandra, Anirban, Singh, Khushbu, Singh, Swati, Sivakumar, Sri, Patra, Ashis K
Format: Article
Language:English
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Summary:A luminescent heterometallic multifunctional theranostic Eu-Pt2 complex [{cis-PtCl2(DMSO)}2Eu(L)(H2O)] has been synthesized, possessing two therapeutic Pt-centers as covalent DNA binders and one emissive Eu(3+)-center which is sensitized by platinum-based metal-to-ligand charge-transfer excited states.
ISSN:1477-9226
1477-9234
DOI:10.1039/c5dt04470g